Volume 26, Number 3—March 2020
CME ACTIVITY - Synopsis
Clinical Characteristics of Disseminated Strongyloidiasis, Japan, 1975–2017
, Masashi Narita, Soichi Shiiki, Yoshihiro Takayama, Shunichi Takakura, and Tomokazu Kishaba
Table 3
Parasitologic investigation and culture results of patients with disseminated strongyloidiasis, Okinawa Chubu Hospital, Uruma, Japan, 1975–2017*
| Characteristic | No. (%) patients |
|||||||
|---|---|---|---|---|---|---|---|---|
| All patients |
Dissemination |
Occult dissemination with meningitis/enteric organisms |
Occult dissemination with culture-negative suppurative meningitis |
|||||
| No. patients |
70 (100) |
32 (45.7) |
12 (17.1) |
26 (37.1) |
||||
| Specimens with larvae† | ||||||||
| Stool | 60 (85.7) | 22 (68.8) | 12 (100) | 26 (100) | ||||
| Sputum | 30 (42.9) | 30 (93.8) | 0 (0) | 0 (0) | ||||
| Gastric juice |
24 (34.3) |
16 (50) |
3 (25) |
5 (19.2) |
||||
| Blood culture results‡ | ||||||||
| Escherichia coli | 6 (8.6) | 4 (12.5) | 2 (16.7) | 0 (0) | ||||
| Klebsiella pneumoniae | 7 (10.0) | 4 (12.5) | 1 (8.3) | 2 (7.7) | ||||
| Streptococcus gallolyticus |
5 (7.1) |
1 (3.1) |
3 (25) |
1 (3.8) |
||||
| CSF culture results‡ | ||||||||
| E. coli | 9/65 (13.8) | 4/27 (14.8) | 5 (41.7) | 0 (0) | ||||
| K. pneumoniae | 6/65 (9.2) | 3/27 (11.1) | 3 (25) | 0 (0) | ||||
| S. gallolyticus | 5/65 (7.7) |
1/27 (3.7) |
4 (33.3) |
0 (0) |
||||
*CSF, cerebrospinal fluid.
†In dissemination, larvae also were detected from ascites (4 cases), urine (3 cases), CSF (2 cases), and skin, bronchoalveolar lavage, and biopsies of the lung, duodenum, and liver (1 case each).
‡In dissemination, blood cultures also were positive for Enterobacter aerogenes, Enterococcus spp., and S. infantarius (1 case each), and CSF cultures were positive for E. aerogenes and Streptococcus spp. (1 case each). In occult dissemination with meningitis (enteric organisms), blood cultures also were positive for E. agglomerans (1 case), and CSF cultures were positive for Enterococcus spp. (1 case).