Volume 26, Number 3—March 2020
Dispatch
Diphtheria Outbreaks in Schools in Central Highland Districts, Vietnam, 2015–2018
Table 2
Epidemiologic link and MLST results for 34 confirmed or epidemiologically linked case-patients with diphtheria, central highlands of Vietnam, 2015–2018*
District | Date of symptom onset | Patient age, y/sex | Epidemiologic link | Vaccine status† | Died | Culture result | PCR | ST | Biotype | Case |
---|---|---|---|---|---|---|---|---|---|---|
Phuoc Son |
2015 Jun 30 | 26/F | Patient 1 | UNK | X | ǂ | ǂ | Linked | ||
2015 Jun 30 | 18/M | UNK | – | § | Linked | |||||
2015 Jul 4 | 17/F | UNK | X | – | § | Linked | ||||
2015 Jul 4 | 27/M | Patient 1’s husband | UNK | + | +§ | 67 | mitis | Confirmed | ||
2015 Jul 4 | 16/M | UNK | – | § | Linked | |||||
2015 Jul 5 | 7/M | Patient 1’s son | UNK | – | § | Linked | ||||
2015 Jul 5 | 20/M | UNK | – | § | Linked | |||||
2015 Jul 8 | 45/M | UNK | – | § | Linked | |||||
2015 Jul 9 | 1/F | UNK | – | § | Linked | |||||
2015 Jul 14 | 14/M | UNK | + | +§ | 67 | mitis | Confirmed | |||
2015 Jul 14 |
9/F |
UNK |
– |
§ |
Linked |
|||||
Tay Giang |
2017 Jan 10 | 16/M | Tay Giang HS |
UNK | X | ǂ | ǂ | Linked | ||
2017 Jan 10 |
17/M |
UNK |
X |
+ |
+ |
243 |
mitis |
Confirmed |
||
Son Tay |
2017 Mar 15 |
13/M |
3 |
X |
+ |
+ |
209 |
mitis |
Confirmed |
|
Tay Giang |
2017 Apr 20 | 7/M | 4 | X | + | + | 243 | mitis | Confirmed | |
2017 Apr 22 | 15/F | UNK | + | + | 243 | mitis | Confirmed | |||
2017 Apr 25 | 7/M | Gari PS | UNK | + | + | 243 | mitis | Confirmed | ||
2017 May 20 | 10/M | Patient 2 (Gari SS) | UNK | + | + | 243 | mitis | Confirmed | ||
2017 May 20 | 10/M | Gari SS | 3 | + | + | 243 | mitis | Confirmed | ||
2017 May 23 |
15/M |
Patient 2’s brother’s friend |
0 |
+ |
+ |
243 |
mitis |
Confirmed |
||
Bac Tra My |
2017 Sep 5 |
5/F |
UNK |
– |
+ |
209 |
Confirmed |
|||
Nam Tra My |
2017 Sep 27 | 12/M | Tra Van SS | UNK | + | + | 209 | mitis | Confirmed | |
2017 Sep 27 | 8/M | Tra Van PS |
0 | X | + | + | 209 | mitis | Confirmed | |
2017 Sep 30 | 9/F | 0 | – | + | 209 | Confirmed | ||||
2017 Sep 30 | 10/F | 0 | – | + | 209 | Confirmed | ||||
2017 Sep 30 | 8/F | 0 | – | + | 209 | Confirmed | ||||
2017 Oct 3 | 11/F | 0 | + | + | 209 | mitis | Confirmed | |||
2017 Oct 3 |
10/M |
0 |
+ |
+ |
209 |
mitis |
Confirmed |
|||
Nam Tra My |
2017 Oct 8 | 12/F | Tra Vinh SS |
UNK | – | + | 67 | Confirmed | ||
2017 Oct 12 |
13/M |
UNK |
+ |
+ |
67 |
mitis |
Confirmed |
|||
Son Tay |
2017 Dec 24 |
3/F |
UNK |
+ |
+ |
244 |
gravis |
Confirmed |
||
Nam Tra My | 2018 Apr 17 | 4/M | Man Di SS | 2 | X | – | + | 67 | intermed | Confirmed |
2018 Apr 24 | 4/M | 3 + 1 SIA | + | + | 67 | Linked | ||||
2018 Apr 24 | 5/F | 1 + 1 SIA | – | + | 67 | Linked |
*Biotypes are of Corynebacterium diphtheriae bacteria. HS, high school; MLST, multilocus sequence typing; SIA, supplemental immunization activity; PS, primary school; SS, secondary school; ST, sequence type; UNK, unknown; –, negative; +, positive.
†The time of last vaccination was infancy or at 1 y of age according to the vaccination program in Vietnam. SIA dose was given October 30, 2017, for the last 2 case-patients.
‡Culture and PCR were not performed for these persons because their samples were not collected.
§PCR was not conducted for these 10 case-patients because this technique was not available during 2015. Stored isolates from 2 culture-positive case-patients were tested by PCR in 2017.