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Volume 26, Number 6—June 2020

Synopsis

Genomic Epidemiology of 2015–2016 Zika Virus Outbreak in Cape Verde

Oumar Faye1, Maria de Lourdes Monteiro1, Bram Vrancken1, Matthieu Prot1, Sebastian Lequime, Maryam Diarra, Oumar Ndiaye, Tomas Valdez, Sandra Tavarez, Jessica Ramos, Silvânia da Veiga Leal, Cecilio Pires, Antonio Moreira, Maria Filomena Tavares, Linete Fernandes, Jorge Noel Barreto, Maria do Céu Teixeira, Maria da Luz de Lima Mendonça, Carolina Cardoso da Silva Leite Gomes, Mariano Salazar Castellon, Laurence Ma, Frédéric Lemoine, Fabiana Gámbaro-Roglia, Déborah Delaune, Gamou Fall, Ibrahima Socé Fall, Mamadou Diop, Anavaj Sakuntabhai, Cheikh Loucoubar, Philippe Lemey, Edward C. Holmes, Ousmane Faye, Amadou Alpha Sall2, and Etienne Simon-Loriere2Comments to Author 
Author affiliations: Institut Pasteur, Dakar, Senegal (Oumar Faye, M. Diarra, O. Ndiaye, G. Fall, M. Diop, C. Loucoubar, Ousmane Faye, A.A. Sall); Ministerio da Saude, Praia, Cape Verde (M. de Lourdes Monteiro, T. Valdez, S. Tavarez, J. Ramos, S. da Veiga Leal, C. Pires, A. Moreira, M.F. Tavares, L. Fernandes, J.N. Barreto, M. do Céu Teixeira, M.L. de Lima Mendonça); Katholieke Universiteit Leuven, Leuven, Belgium (B. Vrancken, S. Lequime, P. Lemey); Institut Pasteur, Paris, France (M. Prot, L. Ma, F. Gámbaro-Roglia, D. Delaune, E. Simon-Loriere); World Health Organization, Praia (C.C. da Silva Leite Gomes, M.S. Castellon, I.S. Fall); CNRS USR 3756, Paris (F. Lemoine); Université de Paris, Sorbonne Paris Cité, Paris (F. Gámbaro-Roglia); Université Paris-Sud/Paris-Saclay, Orsay, France (D. Delaune); Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France (D. Delaune); CNRS UMR 2000, Paris (A. Sakuntabhai); The University of Sydney, Sydney, New South Wales, Australia (E.C. Holmes)

Main Article

Figure 2

Suspected Zika cases, cases tested for Zika virus (ZIKV) infection, ZIKV antibody–positive cases, and ZIKV RNA–positive cases, Cape Verde, 2015–2016, by epidemiologic week. A) Cases of suspected ZIKV infection (n = 7,580) (9). B) Cases tested for ZIKV infection, ZIKV antibody–positive cases, and ZIKV RNA–positive cases. Only 1,226 of 7,580 cases of suspected ZIKV infection are included among those tested for ZIKV infection. In addition, some patients with fever only or rash only who did not fit

Figure 2. Suspected Zika cases, cases tested for Zika virus (ZIKV) infection, ZIKV antibody–positive cases, and ZIKV RNA–positive cases, Cape Verde, 2015–2016, by epidemiologic week. A) Cases of suspected ZIKV infection (n = 7,580) (9). B) Cases tested for ZIKV infection, ZIKV antibody–positive cases, and ZIKV RNA–positive cases. Only 1,226 of 7,580 cases of suspected ZIKV infection are included among those tested for ZIKV infection. In addition, some patients with fever only or rash only who did not fit the Zika case definition were also tested for ZIKV infection and included on this graph. ZIKV IgG–positive cases were negative by qRT-PCR and IgM ELISA and confirmed positive for ZIKV IgG by plaque reduction neutralization test. Arrows indicate the time of patient sampling for the 3 sequenced ZIKV isolates (GenBank accession nos. MK241415–7). qRT-PCR, quantitative reverse transcription PCR; –, negative; +, positive.

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1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: May 18, 2020
Page updated: May 18, 2020
Page reviewed: May 18, 2020
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