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Volume 26, Number 6—June 2020

Research

Failures of 13-Valent Conjugated Pneumococcal Vaccine in Age-Appropriately Vaccinated Children 2–59 Months of Age, Spain

Sergi HernándezComments to Author , Fernando Moraga-Llop, Alvaro Díaz, Mariona F. de Sevilla, Pilar Ciruela, Carmen Muñoz-Almagro, Gemma Codina, Magda Campins, Juan José García-García, Cristina Esteva, Conchita Izquierdo, Sebastià González-Peris, Johanna Martínez-Osorio, Sonia Uriona, Luis Salleras, and Ángela Domínguez
Author affiliations: Agència de Salut Pública de Catalunya, Generalitat de Catalunya, Barcelona, Spain (S. Hernández, P. Ciruela, C. Izquierdo); Hospital Universitari Vall d’Hebron, Barcelona (F. Moraga-Llop, M. Campins, S. González-Peris); Hospital de Nens, Barcelona (A. Díaz); Hospital Sant Joan de Déu Barcelona, Barcelona (M.F. de Sevilla, C. Muñoz-Almagro, J.J. García-García, C. Esteva, J. Martínez-Osorio); Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Spain (M.F. de Sevilla, C. Muñoz-Almagro, J.J. García-García); CIBER de Epidemiología y Salud Pública, Madrid, Spain (P. Ciruela, J.J. García-García, C. Esteva, L. Salleras, Á. Domínguez); Universitat Internacional de Catalunya, Barcelona (C. Muñoz-Almagro); Vall d’Hebron Institut de Recerca, Barcelona (M. Campins, S. Uriona); Universitat de Barcelona, Barcelona (L. Salleras, Á. Domínguez)

Main Article

Table 2

Distribution of PCV13 serotypes causing invasive pneumococcal disease in patients 2–59 months of age in cases of vaccine failure and in unvaccinated patients, Catalonia, Spain, 2012–2016

PCV13 serotype Vaccine failure, no. (%), n = 24 Unvaccinated patients, no. (%) n = 72 OR (95% CI) p value
1 1 (4.2) 16 (22.2) 0.15 (0.02–1.21) 0.062
3 16 (66.7) 20 (27.8) 5.20 (1.93–14.04) 0.001
6A 0 1 (1.4) 0 0
6B 1 (4.2) 1 (1.4) 3.09 (0.19–51.35) 0.439
7F 0 3 (4.2) 0 0
9V 0 3 (4.2) 0 0
14 1 (4.2) 12 (16.7) 0.22 (0.03–1.77) 0.174
18C 0 1 (1.4) 0 0
19A 5 (20.8) 12 (16.7) 1.32 (0.41–4.21) 0.634
19F 0 2 (2.8) 0 0
23F 0 1 (1.4) 0 0

Main Article

Page created: May 18, 2020
Page updated: May 18, 2020
Page reviewed: May 18, 2020
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