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Volume 26, Number 8—August 2020
Research

Presence of Segmented Flavivirus Infections in North America

Kurt J. Vandegrift1, Arvind Kumar1, Himanshu Sharma, Satyapramod Murthy, Laura D. Kramer, Richard Ostfeld, Peter J. Hudson, and Amit KapoorComments to Author 
Author affiliations: Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, Pennsylvania, USA (K.J. Vandegrift, P.J. Hudson); Center for Vaccines and Immunity, The Research Institute at Nationwide Children’s Hospital, Columbus, Ohio, USA (A. Kumar, H. Sharma, S. Murthy, A. Kapoor); Wadsworth Center, New York State Department of Health, Albany, New York, USA (L.D. Kramer); University of Albany-SUNY School of Public Health, Albany (L.D. Kramer); Cary Institute of Ecosystem Studies, Millbrook, New York, USA (R. Ostfeld); Ohio State University College of Medicine and Public Health, Columbus (A. Kapoor)

Main Article

Table

Percentages of pairwise amino acid distances between NS5 protein of FLSV-US and known JMTV-like viruses on the basis of the NS5 protein region corresponding to aa positions 55 to 913 on JMTV reference sequence YP_009029999.1

Sequence
ID*
A†
B
C
D
E
F
G
H
I
J
K
L
M
N
FLSV-US NS5† A
AOD41697 JMTV B 31.2
AVL26136 AMBV C 31.8 2.8
AXE71873 ALSV D 34.7 19.6 19.8
AXH37995 JMTV E 34.7 7 7.3 19.4
AXH37997 JMTV F 32.2 6.9 7.2 19.4 0.1
AYV61016 JMTV G 31.5 2.8 2.9 19 6.8 6.6
AYV61021 JMTV H 31.8 4 4.3 19.4 7.3 7.2 3.1
AYV61033 JMTV I 31.9 4.1 4.4 19.3 7.2 7.1 3.3 0.6
QBQ65056 YTV J 33.4 20.4 20.5 18.3 20.1 20.1 20.1 20 19.9
QCB64647 RFLV K 31.5 2.4 1.5 19.1 6.4 6.3 2.3 3.4 3.5 19.9
QCW07567 KTV L 31.7 3.5 3.6 19.4 7.2 7.1 2.6 2.9 3 20.4 3
YP_009029999 JMTV M 31.8 3.7 2.3 19.6 7.2 7.1 3.4 4.4 4.4 20.4 2.2 3.7
YP_009351917 MTV N 30.8 3.7 3.8 19.7 6.9 6.8 2.4 2.7 2.8 20.4 3.5 2.7 4.2

ALSV, Alongshan virus; AMBV, Amblyomma virus; ID, sequence identifier; JMTV, Jingmen tick virus; KYV, Kindia tick virus; MTV, Mogiana tick virus; RFLV, Rhipicephalus flavi-like virus; YTV, Yanggou tick virus.
†Virus identified in Pennsylvania, USA, as part of this study.
*Identifiers A–N in the top row represent the corresponding A-Z sequences in the left-hand column.

Main Article

1These authors contributed equally to this article.

Page created: May 14, 2020
Page updated: July 21, 2020
Page reviewed: July 21, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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