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Volume 26, Number 8—August 2020
Research Letter

mcr-Positive Escherichia coli ST131-H22 from Poultry in Brazil

Andre Becker S. SaidenbergComments to Author , Marc Stegger, Lance Bradley Price, Thor Bech Johannesen, Maliha Aziz, Marcos P.V. Cunha, Andrea M. Moreno, and Terezinha Knöbl
Author affiliations: University of São Paulo, São Paulo, Brazil (A.B.S. Saidenberg, M.P.V. Cunha, A.M. Moreno, T. Knöbl); George Washington University, Washington, DC, USA (M. Stegger, L.B. Price, M. Aziz); Statens Serum Institut, Copenhagen, Denmark (M. Stegger, T.B. Johannesen)

Main Article

Figure

Phylogenetic analysis of Escherichia coli ST131-H22 isolates from poultry in Brazil and reference sequences. A) Unrooted phylogeny of 146 E. coli ST131-H22 isolates based on core genome single-nucleotide polymorphisms with the host origin outlined. The cluster containing closely related isolates to the 6 isolates from Brazil is highlighted. B) Rooted phylogeny of closely related isolates from retail meat with APEC and a human isolate with our 6 APEC isolates. The highlighted cluster include a pa

Figure. Phylogenetic analysis of Escherichia coli ST131-H22 isolates from poultry in Brazil and reference sequences. A) Unrooted phylogeny of 146 E. coli ST131-H22 isolates based on core genome single-nucleotide polymorphisms with the host origin outlined. The cluster containing closely related isolates to the 6 isolates from Brazil is highlighted. B) Rooted phylogeny of closely related isolates from retail meat with APEC and a human isolate with our 6 APEC isolates. The highlighted cluster includes a partial depiction of the tree including the data on host, country, and disease (urinary tract infection or other). Clusters containing the study’s isolates have their individual identification in parenthesis. Asterisks indicate farm origins (*, farm 1; **, farm 2). Virulence factors profiles are identified as groups A: cvi/cva, ent, fimA-H, ibeA, irp1/2, iroN, iucD,iss, kpsM, ompA, tsh; B: cvi/cva, ent, fimA-H, ibeA, irp1/2, iroN, iucD, iss, kpsM, ompA; and C: cvi/cva, ent, fimA-H, fyuA, ibeA, irp1/2, iroN, iucD, iss, kpsM, ompA, tsh. Plasmid profiles are identified by group: 1: IncFIB, IncFIC(FII), Incl1; 2: IncFIB, IncFIC(FII), IncFII, Incl1; 3: IncFIB, IncFIC(FII), IncFII, IncHI2, IncHI2A, Incl1; 4: IncFIB, IncFIC(FII), Incl1, IncN; 5: IncFIB, IncFIC(FII), IncFII, IncFII(pCoo), IncHI2, IncHI2A; 6: IncFIB, IncFIC(FII), IncFII, IncHI2, IncHI2A; 7: IncFIB, IncFII, Incl1, IncX1; and 8: IncFIB, IncFIC(FII), IncFII, Incl1, IncX1. Phenotypic colistin-resistance is indicated by the symbol # for the 2 colistin-resistance mcr genes positive isolates, showing resistance according to 2018 Clinical Laboratory Standards Institute (https://clsi.org/) clinical breakpoints. APEC, avian pathogenic E. coli; ID, identification; ST, sequence type; UTI, urinary tract infection.

Main Article

Page created: April 18, 2020
Page updated: July 18, 2020
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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