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Volume 26, Number 9—September 2020

Risk-Based Estimate of Human Fungal Disease Burden, China

Ling-Hong Zhou1, Ying-Kui Jiang1, Ruo-Yu Li, Li-Ping Huang, Ching-Wan Yip, David W. Denning2, and Li-Ping Zhu2Comments to Author 
Author affiliations: Huashan Hospital, Shanghai, China; and Fudan University, Shanghai (L.-H. Zhou, Y.-K. Jiang, L.-P. Huang, C.-W. Yip, L.-P. Zhu); Peking University First Hospital, Beijing, China (R.-Y. Li); Peking University, Beijing (R.-Y. Li); National Clinical Research Center for Skin and Immune Diseases, Beijing (R.-Y. Li); Wythenshawe Hospital, Manchester, UK (D.W. Denning); University of Manchester, Manchester (D.W. Denning); Global Action Fund for Fungal Infections, Geneva, Switzerland (D.W. Denning)

Main Article

Table 1

Population characteristics in China, by age, gender, high-risk factors, and underlying diseases*

Population characteristic No., in thousands Reference
Total population 1,433,784 UN, 2019 (9)
Population of children 0–14 y 254,930 UN, 2020 (9)
Female population, 15–49 y 403,377 UN, 2020 (9)
Population >40 y 688,074 UN, 2020 (9)
People living with HIV 810 UNAIDS, 2017 (10)
Proportion of HIV patients on ART 40% UNAIDS, 2017 (10)
Adults living with HIV and CD4 <200 cells/µL 106 Assumes a 5-y decline in immunity
AIDS related deaths 26 UNAIDS, 2017 (10)
Annual cases of TB 856 WHO 2017 (11)
Annual cases of pulmonary TB who survive 844 WHO 2017 (11)
Adults with asthma (4.2%) population 49,512 Huang, 2019 (13)
Adults with COPD (7.2% of population) 102,377 Zhu, 2018 (14)
Adults with COPD admitted to hospital each year (20.1%) 29,382 Zhu, 2018 (14)
Lung cancer 774.3 GLOBOCAN, 2018 (1)
Liver transplants per year 4.73 COTR (12)
Renal transplants per year 10.8 COTR (12)
Lung transplants per year 0.3 COTR (12)
Heart transplants per year 0.56 COTR (12)
Allogeneic stem cell transplants per year 5.0 Xu, 2016 (15)
Acute myelogenous leukemia 41.2 40% of GLOBOCAN leukemia and multiple myeloma total, 2018 (1)
No. patients on peritoneal dialysis 73.9 Wilkie and Davies, 2017 (16)
Intensive care unit beds 86.0 Murthy, 2012 (17)
Intensive care admissions surviving >24 h 5,126 Du, 2013 (18)

*ART, antiretroviral therapy; COPD, chronic obstructive pulmonary disease; COTR, China Organ Transplantation Registration System; TB, tuberculosis;
UN, United Nations Population Division; UNAIDS, the Joint Nations Program on HIV/AIDS; WHO, World Health Organization.

Main Article

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Main Article

1These authors contributed equally to this article.

2These authors contributed equally to this article.

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