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Volume 27, Number 1—January 2021
Research

Viral Metagenomic Analysis of Cerebrospinal Fluid from Patients with Acute Central Nervous System Infections of Unknown Origin, Vietnam

Nguyen To AnhComments to Author , Le Nguyen Truc Nhu, Nguyen Thi Thu Hong, Tran My Phuc, Pham Thi Thanh Tam, Dang Thao Huong, Tran Tuan Anh, Xutao Deng, Ho Dang Trung Nghia, Tran Thua Nguyen, Nguyen Van Hung, Nguyen Dac Thuan, Pham Thi Hong Phuong, Nguyen Van Vinh Chau, Stephen Baker, Eric Delwart, Guy Thwaites, Le Van TanComments to Author , and for the VIZIONS Consortium1
Author affiliations: Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam (N.T. Anh, L.N.T. Nhu, N.T.T. Hong, T.M. Phuc, P.T.T. Tam, D.T. Huong, T.T. Anh, H.D.T. Nghia, G. Thwaites, L.V. Tan); Hue Central Hospital, Hue City, Vietnam (T.T. Nguyen); Dak Lak General Hospital, Ban Me Thuot City, Vietnam (N.V. Hung); Khanh Hoa General Hospital, Nha Trang City, Vietnam (N.D. Thuan); Dong Thap General Hospital, Dong Thap, Vietnam (P.T.H. Phuong); Vitalant Research Institute, San Francisco, California, USA (X. Deng, E. Delwart); University of California Department of Laboratory Medicine, San Francisco (X. Deng, E. Delwart); Pham Ngoc Thach University, Ho Chi Minh City (H.D.T. Nghia); Hospital for Tropical Diseases, Ho Chi Minh City (N.V.V. Chau); University of Cambridge Institute of Therapeutic Immunology and Infectious Disease, Cambridge, UK (S. Baker); Centre for Tropical Medicine, Nuffield Department of Medicine, University of Oxford, Oxford, UK (S. Baker, G. Thwaites)

Main Article

Figure 2

Number of cerebrospinal fluid samples with detected viruses by metagenomic next-generation sequencing and then confirmed by virus-specific PCR or reverse-transcription PCR, Vietnam, December 2012–October 2016. Samples were collected from patients with suspected central nervous system infection. For human papillomavirus, confirmatory testing was not performed because of the unavailability of a PCR assay.

Figure 2. Number of cerebrospinal fluid samples with detected viruses by metagenomic next-generation sequencing and then confirmed by virus-specific PCR or reverse-transcription PCR, Vietnam, December 2012–October 2016. Samples were collected from patients with suspected central nervous system infection. For human papillomavirus, confirmatory testing was not performed because of the unavailability of a PCR assay.

Main Article

1Members are listed at the end of this article.

Page created: November 24, 2020
Page updated: December 21, 2020
Page reviewed: December 21, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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