Detection of Norovirus Variant GII.4 Hong Kong in Asia and Europe, 2017−2019
Martin Chi-Wai Chan
1, Sunando Roy, Joseph Bonifacio, Lin-Yao Zhang, Preeti Chhabra, Jenny C.M. Chan, Cristina Celma, Mary Ann Igoy, Sin-Leung Lau, Kirran N. Mohammad, Jan Vinjé, Harry Vennema, Judith Breuer, Marion Koopmans, Miranda de Graaf

, and
for NOROPATROL2
Author affiliations: The Chinese University of Hong Kong, Hong Kong, China (M.C.-W. Chan, L.-Y. Zhang, J.C.M. Chan, S.-L. Lau, K.N. Mohammad); University College London, London, UK (S. Roy, J. Breuer); Research Institute for Tropical Medicine, Muntinlupa City, the Philippines (J. Bonifacio, M.A. Igoy); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (P. Chhabra, J. Vinjé); Public Health England, London (C. Celma); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (H. Vennema); Erasmus Medical Center, Rotterdam, the Netherlands (M. Koopmans, M. de Graaf)
Main Article
Table 2
Amino acids on the major capsid protein at 5 positions proposed to be influential in the emergence and replacement of pandemic norovirus GII.4 variants since 1995*
GII.4 variant |
Amino acid position
|
352 |
355 |
357 |
368 |
378 |
Hong Kong |
S |
A |
D |
G |
G |
Osaka |
L |
S |
D |
A |
G |
Sydney 2012 |
Y |
S |
D |
E |
N |
New Orleans 2009 |
Y |
S |
D |
A |
N |
Den Haag 2006 |
Y |
S |
P |
S |
H |
Hunter 2004 |
S |
S |
H |
S |
G |
Farmington Hills 2002 |
S |
D |
H |
N |
G |
US 1995–96 |
S |
S |
H |
T |
G |
Main Article
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