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Volume 27, Number 1—January 2021
Dispatch

Detection of Norovirus Variant GII.4 Hong Kong in Asia and Europe, 2017−2019

Martin Chi-Wai Chan1, Sunando Roy, Joseph Bonifacio, Lin-Yao Zhang, Preeti Chhabra, Jenny C.M. Chan, Cristina Celma, Mary Ann Igoy, Sin-Leung Lau, Kirran N. Mohammad, Jan Vinjé, Harry Vennema, Judith Breuer, Marion Koopmans, Miranda de GraafComments to Author , and for NOROPATROL2
Author affiliations: The Chinese University of Hong Kong, Hong Kong, China (M.C.-W. Chan, L.-Y. Zhang, J.C.M. Chan, S.-L. Lau, K.N. Mohammad); University College London, London, UK (S. Roy, J. Breuer); Research Institute for Tropical Medicine, Muntinlupa City, the Philippines (J. Bonifacio, M.A. Igoy); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (P. Chhabra, J. Vinjé); Public Health England, London (C. Celma); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (H. Vennema); Erasmus Medical Center, Rotterdam, the Netherlands (M. Koopmans, M. de Graaf)

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Table 2

Amino acids on the major capsid protein at 5 positions proposed to be influential in the emergence and replacement of pandemic norovirus GII.4 variants since 1995*

GII.4 variant Amino acid position
352 355 357 368 378
Hong Kong S A D G G
Osaka L S D A G
Sydney 2012 Y S D E N
New Orleans 2009 Y S D A N
Den Haag 2006 Y S P S H
Hunter 2004 S S H S G
Farmington Hills 2002 S D H N G
US 1995–96 S S H T G

*GII.4 variants with pandemic spread are annotated with the year of predominance (e.g., Sydney 2012). Amino acids are shown by 1-letter codes and color-coded to show variations. Source: (7).

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References
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1Current affiliation: Research Office, Food and Health Bureau, Hong Kong, China.

2Members who contributed data are listed at the end of this article.

Page created: November 19, 2020
Page updated: December 21, 2020
Page reviewed: December 21, 2020
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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