Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 27, Number 10—October 2021
Research

Risk Assessment for Highly Pathogenic Avian Influenza A(H5N6/H5N8) Clade 2.3.4.4 Viruses

Christine H.T. Bui1, Denise I.T. Kuok1, Hin Wo Yeung, Ka-Chun Ng, Daniel K.W. Chu, Richard J. Webby, John M. Nicholls, J.S. Malik Peiris, Kenrie P.Y. Hui, and Michael C.W. ChanComments to Author 
Author affiliations: The University of Hong Kong, Hong Kong, China (C.H.T. Bui, D.I.T. Kuok, H.W. Yeung, K.-C. Ng, D.K.W. Chu, J.M. Nicholls, J.S.M. Peiris, K.P.Y. Hui, M.C.W. Chan); St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (R.J. Webby)

Main Article

Table

Effects of desialylation on influenza A virus hemagglutination of turkey red blood cells*

Virus 0.5% Turkey red blood cells
Untreated Sialidase S† Sialidase C†
Influenza A(H1N1)pdm09 64 64 8
HPAI H5N1/483 256 0 0
HPAI H5N1/SZ1 64 4 4
HPAI H5N6/39715 128 0 0
avHPAI H5N6/DK01 128 128 32
avHPAI H5N6/18259 64 4 4
avHPAI H5N6/MP692 64 64 32
avHPAI H5N8/636099 128 128 8
avHPAI H5N8/642613 256 256 64
avLPAI H5N8/MP5883 32 4 4

*Hemagglutination titers were calculated as the reciprocal of the highest dilution that gave hemagglutination. Experiments were performed in triplicate and led to identical results. Av, avian; HPAI, highly pathogenic avian influenza. †Agilent (https://www.agilent.com).

Main Article

1These first authors contributed equally to this article.

Page created: July 30, 2021
Page updated: September 19, 2021
Page reviewed: September 19, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external