Population Genomics and Inference of Mycobacterium avium Complex Clusters in Cystic Fibrosis Care Centers, United States
Nabeeh A. Hasan1
, Rebecca M. Davidson1
, L. Elaine Epperson, Sara M. Kammlade, Sean Beagle, Adrah R. Levin, Vinicius Calado de Moura, Joshua J. Hunkins, Natalia Weakly, Scott D. Sagel, Stacey L. Martiniano, Max Salfinger, Charles L. Daley, Jerry A. Nick, and Michael Strong
Author affiliations: National Jewish Health, Denver, Colorado, USA (N.A. Hasan, R.M. Davidson, L.E. Epperson, S.M. Kammlade, S. Beagle, A.R. Levin, V. Calado de Moura, J.J. Hunkins, N. Weakly, C.L. Daley, J.A. Nick, M. Strong); University of Colorado Anschutz Medical Campus and Children’s Hospital Colorado, Aurora, Colorado, USA (S.D. Sagel, S.L. Martiniano); University of South Florida College of Public Health and Morsani College of Medicine, Tampa, Florida, USA (M. Salfinger)
Figure 4. Phylogenetic relationships in a study of Mycobacterium avium complex isolates in cystic fibrosis care centers, United States. A) Phylogenetic tree of 207 M. avium isolates showing the relationships between M. avium cystic fibrosis care center and select non–cystic fibrosis, environmental, and zoonotic isolates. B). Phylogenetic tree of 235 isolates showing the relationships between cystic fibrosis care center and select non–cystic fibrosis M. intracellulare subsp. chimaera and M. intracellulare subsp. intracellulare isolates. Former species M. yongonense type strain 05–1380T was also included as part of M. intracellulare subsp. chimaera to reflect current taxonomy. SNP, single-nucleotide polymorphism.
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