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Volume 27, Number 11—November 2021
Research

Genomic Profiling of Mycobacterium tuberculosis Strains, Myanmar

Htin Lin Aung1Comments to Author , Wint Wint Nyunt1, Yang Fong, Patrick J. Biggs, Richard C. Winkworth, Peter J. Lockhart, Tsin Wen Yeo, Philip C. Hill, Gregory M. Cook, and Si Thu Aung
Author affiliations: University of Otago, Dunedin, New Zealand (H.L. Aung, P.C. Hill, G.M. Cook); Ministry of Health and Sports, Yangon, Myanmar (W.W. Nyunt); Massey University, Palmerston North, New Zealand (Y. Fong, P.J. Biggs, R.C. Winkworth, P.J. Lockhart); Nanyang Technological University, Singapore (T.W. Yeo); Ministry of Health and Sports, Naypyitaw, Myanmar (S.T. Aung)

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Figure 3

Maximum-likelihood tree based on whole-genome analysis of 309 Mycobacterium tuberculosis strains from Myanmar. Lineages and drug resistance status of isolates are shown. MDR indicates multidrug-resistant to 2 first-line drugs (isoniazid and rifampin); pre-MDR, resistant to 1 of 2 first-line drugs (isoniazid or rifampicin); pre-XDR, resistant to fluoroquinolones or injectable drugs in addition to MDR; XDR, resistant to fluoroquinolones and injectable drugs, in addition to MDR. Scale bar indicates nucleotide substitutions per site. MDR, multidrug resistant; XDR, extensively drug resistant.

Figure 3. Maximum-likelihood tree based on whole-genome analysis of 309 Mycobacterium tuberculosis strains from Myanmar. Lineages and drug resistance status of isolates are shown. MDR indicates multidrug-resistant to 2 first-line drugs (isoniazid and rifampin); pre-MDR, resistant to 1 of 2 first-line drugs (isoniazid or rifampicin); pre-XDR, resistant to fluoroquinolones or injectable drugs in addition to MDR; XDR, resistant to fluoroquinolones and injectable drugs, in addition to MDR. Scale bar indicates nucleotide substitutions per site. MDR, multidrug resistant; XDR, extensively drug resistant.

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1These authors contributed equally to this article.

Page created: July 13, 2021
Page updated: October 19, 2021
Page reviewed: October 19, 2021
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