Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 27, Number 11—November 2021
Research

Genomic Profiling of Mycobacterium tuberculosis Strains, Myanmar

Htin Lin Aung1Comments to Author , Wint Wint Nyunt1, Yang Fong, Patrick J. Biggs, Richard C. Winkworth, Peter J. Lockhart, Tsin Wen Yeo, Philip C. Hill, Gregory M. Cook, and Si Thu Aung
Author affiliations: University of Otago, Dunedin, New Zealand (H.L. Aung, P.C. Hill, G.M. Cook); Ministry of Health and Sports, Yangon, Myanmar (W.W. Nyunt); Massey University, Palmerston North, New Zealand (Y. Fong, P.J. Biggs, R.C. Winkworth, P.J. Lockhart); Nanyang Technological University, Singapore (T.W. Yeo); Ministry of Health and Sports, Naypyitaw, Myanmar (S.T. Aung)

Main Article

Figure 4

Maximum-likelihood tree of Mycobacterium tuberculosis strains, Myanmar, within 9 clusters and their drug resistance profiles. Dotted lines indicate boundaries of individual clusters. An outgroup (#108) differs by >100 single-nucleotide polymorphisms from the strains within 9 clusters. N, E, and W indicate the North, East, and West Districts of Yangon, respectively. MDR, resistant to 2 first-line drugs (isoniazid and rifampin); pre-MDR, resistant to 1 of 2 first-line drugs (isoniazid or rifampicin); pre-XDR, resistant to fluoroquinolones or injectable drugs in addition to MDR; XDR, resistant to fluoroquinolones and injectable drugs, in addition to MDR. AMG, aminoglycosides; ETH, ethambutol; FQ, fluoroquinolones; INH, isoniazid; RIF, rifampin; STR, streptomycin. Scale bar indicates nucleotide substitutions per site.

Figure 4. Maximum-likelihood tree of Mycobacterium tuberculosis strains, Myanmar, within 9 clusters and their drug resistance profiles. Dotted lines indicate boundaries of individual clusters. An outgroup (#108) differs by >100 single-nucleotide polymorphisms from the strains within 9 clusters. N, E, and W indicate the North, East, and West Districts of Yangon, respectively. MDR, resistant to 2 first-line drugs (isoniazid and rifampin); pre-MDR, resistant to 1 of 2 first-line drugs (isoniazid or rifampicin); pre-XDR, resistant to fluoroquinolones or injectable drugs in addition to MDR; XDR, resistant to fluoroquinolones and injectable drugs, in addition to MDR. AMG, aminoglycosides; ETH, ethambutol; FQ, fluoroquinolones; INH, isoniazid; RIF, rifampin; STR, streptomycin. Scale bar indicates nucleotide substitutions per site.

Main Article

1These authors contributed equally to this article.

Page created: July 13, 2021
Page updated: October 19, 2021
Page reviewed: October 19, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external