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Volume 27, Number 11—November 2021
Research Letter

Fatal Systemic Capillary Leak Syndrome after SARS-CoV-2 Vaccination in Patient with Multiple Myeloma

Gwang-Jun Choi, Seon Ha Baek, Junmo Kim, Jung Ho Kim, Geun-Yong Kwon, Dong Keun Kim, Yeon Haw Jung, and Sejoong KimComments to Author 
Author affiliations: Daegu Metropolitan Government, Daegu, South Korea (G.-J. Choi); Hallym University Dongtan Sacred Heart Hospital, Hwaseong, South Korea (S.H. Baek); National Forensic Service Daegu Institute, Daegu (J. Kim); Yeungnam University College of Medicine, Daegu (J.H. Kim); Korea Disease Control and Prevention Agency, Cheongju, South Korea (G.-Y. Kwon, D.K. Kim, Y.H. Jung); Seoul National University Bundang Hospital, Seongnam, South Korea (S. Kim)

Main Article


Results of laboratory tests in patient with smoldering multiple myeloma who had SCLS develop after vaccination for severe acute respiratory syndrome coronavirus, South Korea*

Clinical measures Reference range Test results after SCLS episodes
5 mo earlier Postvaccination
Leukocytes, ×103/mm3 4–10 6.88 29.42
Hemoglobin, g/dL 13–17 14.7 22.7
Hematocrit, % 40–52 44.3 63.7
Platelet, ×103/mm3 140–440 259 133
Albumin, g/dL 3.5–5.0 4.8 3.3
Blood urea nitrogen, mg/dL 8–23 13.6 33
Creatinine, mg/dL 0.7–1.2 0.94 2.0
Aspartate transaminase, IU/L 10–35 22 30
Alanine transferase, IU/L 0–40 14 4
Total bilirubin, mg/dL 0.1–1.2 0.5 1.46
Calcium, mg/dL 8.6–10.6 10.0 8.9
Erythrocyte sedimentation rate, mm/h 0–20 Not done 13
C-reactive protein, mg/dL 0–0.5 Not done 2.371
Procalcitonin, ng/ml 0–5 Not done 0.641
Troponin I, ng/mL 0–0.04 Not done 0.017
Creatine kinase myocardial band, ng/mL 0.6–6.3 Not done 3.5
N terminal-pro B-type natriuretic peptide, pg/mL 0–125 35.1 4,427
Lactic acid, mmol/L 0.5–1.6 Not done 5.4
Creatine phosphokinase, IU/L 1–171 Not done 276

*Vaccine was Ad26.COV2.S (Johnson & Johnson/Janssen, SCLS, systemic capillary leak syndrome.

Main Article

Page created: August 24, 2021
Page updated: October 19, 2021
Page reviewed: October 19, 2021
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