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Volume 27, Number 2—February 2021
Research

Hepatitis C Virus Transmission Clusters in Public Health and Correctional Settings, Wisconsin, USA, 2016–20171

Karli R. Hochstatter2Comments to Author , Damien C. Tully2, Karen A. Power, Ruth Koepke, Wajiha Z. Akhtar, Audrey F. Prieve, Thomas Whyte, David J. Bean, David W. Seal, Todd M. Allen3, and Ryan P. Westergaard3
Author affiliations: University, New York, New York, USA (K.R. Hochstatter); University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA (K.R. Hochstatter, R. Koepke, W.Z. Akhtar, R.P. Westergaard); London School of Hygiene and Tropical Medicine, London, UK (D.C. Tully); Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA (D.C. Tully, K.A. Power, D.J. Bean, T.M. Allen); Wisconsin Department of Health Services, Madison (R. Koepke, R.P. Westergaard); Wisconsin State Laboratory of Hygiene, Madison (A.F. Prieve, T. Whyte); Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA (D.W. Seal)

Main Article

Figure 2

Hepatitis C virus (HCV) transmission network among persons in public health and corrections settings, Wisconsin, USA, 2016–2017, showing 42 clusters identified by Global Hepatitis Outbreak and Surveillance Technology (GHOST). Each node represents an HCV-infected person for whom HCV sequence data were generated. A transmission link is denoted as a line connecting persons where the minimal Hamming distance between sequences is smaller than the previously validated genetic threshold of 3.77%. Lines connecting clusters are colored according to genotype.

Figure 2. Hepatitis C virus (HCV) transmission network among persons in public health and corrections settings, Wisconsin, USA, 2016–2017, showing 42 clusters identified by Global Hepatitis Outbreak and Surveillance Technology (GHOST). Each node represents an HCV-infected person for whom HCV sequence data were generated. A transmission link is denoted as a line connecting persons where the minimal Hamming distance between sequences is smaller than the previously validated genetic threshold of 3.77%. Lines connecting clusters are colored according to genotype.

Main Article

1The methods described in this article, along with preliminary results from the first 231 specimens analyzed, were presented in poster format at the 8th International Conference on Hepatitis Care in Substance Users; 2019 Sep 11–13; Montreal, Quebec, Canada.

2These first authors contributed equally to this article.

3These senior authors contributed equally to this article.

Page created: December 07, 2020
Page updated: January 23, 2021
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