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Volume 27, Number 3—March 2021
Dispatch

Bedaquiline as Treatment for Disseminated Nontuberculous Mycobacteria Infection in 2 Patients Co-Infected with HIV

Eliza GilComments to Author , Nicola Sweeney, Veronica Barrett, Stephen Morris-Jones, Robert F. Miller, Victoria J. Johnston, and Michael Brown
Author affiliations: University College London Hospitals, National Health Service Foundation Trust, London, UK (E. Gil, N. Sweeney, V. Barrett, S. Morris-Jones, V.J. Johnston, M. Brown); Central and North West London National Health Service Foundation Trust, London (R.F. Miller); University College London, London (R.F. Miller); London School of Hygiene and Tropical Medicine, London (R.F. Miller, V.J. Johnston, M. Brown)

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Figure 1

Summary of treatment and monitoring of 2 HIV-positive persons who had disseminated Mycobacterium abscessus infections, London, UK. A) Case-patient 1. B) Case-patient 2. The infection in case-patient 1 was secondary to fecal abdominal cavity contamination after rectal perforation. Bars in top section show timing of treatments; red indicates bedaquiline. Drug regimens and treatment responses were measured by using Hb (g/L), Neut (× 109 cells/L), and CRP (mg/L). Values (+ and –) on the bottom of panel B are results for mycobacterial blood cultures. CRP, C-reactive protein; Hb, hemoglobin; Neut, neutrophils.

Figure 1. Summary of treatment and monitoring of 2 HIV-positive persons who had disseminated Mycobacterium abscessus infections, London, UK. A) Case-patient 1. B) Case-patient 2. The infection in case-patient 1 was secondary to fecal abdominal cavity contamination after rectal perforation. Bars in top section show timing of treatments; red indicates bedaquiline. Drug regimens and treatment responses were measured by using Hb (g/L), Neut (× 109 cells/L), and CRP (mg/L). Values (+ and –) on the bottom of panel B are results for mycobacterial blood cultures. CRP, C-reactive protein; Hb, hemoglobin; Neut, neutrophils.

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Page created: November 11, 2020
Page updated: February 21, 2021
Page reviewed: February 21, 2021
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