Volume 27, Number 3—March 2021
Synopsis
Decentralized Care for Rifampin-Resistant Tuberculosis, Western Cape, South Africa
Table 4
Multivariable logistic regression for factors associated with sample submitted from a TB hospital <1 y after diagnosis of RR TB, Western Cape, South Africa, 2012–2014*
Characteristic | Overall, n = 2,831 |
Cape Town, n = 1,846 |
Outside Cape Town, n = 985 |
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---|---|---|---|---|---|---|---|---|
OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |||
Location | ||||||||
Cape Town | Referent | Referent | Referent | |||||
Other |
5.7 (4.8–6.8) |
<0.01 |
NA |
NA |
||||
Sex | ||||||||
F | Referent | Referent | Referent | |||||
M |
1.2 (1.0–1.4) |
0.03 |
1.2 (1.0–1.5) |
0.07 |
1.2 (0.9–1.6) |
0.27 |
||
Age, y | ||||||||
15–34 | Referent | Referent | Referent | |||||
35–54 | 1.1 (0.9–1.3) | 0.43 | 1.2 (0.9–1.5) | 0.14 | 0.9 (0.7–1.3) | 0.55 | ||
>55 |
0.8 (0.6–1.2) |
0.24 |
1.0 (0.6–1.6) |
0.95 |
0.6 (0.3–1.0) |
0.05 |
||
Type of TB | ||||||||
Pulmonary only | Referent | Referent | Referent | |||||
Extrapulmonary only | 1.0 (0.5–1.7) | 0.98 | 0.8 (0.4–1.7) | 0.63 | 1.3 (0.5–3.5) | 0.53 | ||
Both |
2.7 (1.8–4.2) |
<0.01 |
3.7 (2.3–5.9) |
<0.01 |
1.1 (0.5–2.4) |
0.85 |
||
Results of most recent smear from <30 d of first RR TB–positive sample | ||||||||
Negative | Referent | Referent | Referent | |||||
Scanty positive | 1.4 (1.0–1.8) | 0.03 | 1.7 (1.2–2.4) | <0.01 | 1.0 (0.6–1.6) | >0.99 | ||
Positive + | 1.5 (1.1–2.1) | <0.01 | 1.6 (1.1–2.2) | 0.02 | 1.5 (0.9–2.8) | 0.16 | ||
Positive ++ | 1.8 (1.3–2.5) | <0.01 | 1.5 (1.0–2.3) | 0.06 | 3.0 (1.5–6.4) | <0.01 | ||
Positive +++ | 2.1 (1.7–2.7) | <0.01 | 1.9 (1.4–2.5) | <0.01 | 3.5 (2.2–5.8) | <0.01 | ||
Unknown |
1.2 (0.9–1.7) |
0.19 |
1.2 (0.8–1.9) |
0.29 |
1.2 (0.7–2.1) |
0.56 |
||
Quarter of RR TB diagnosis† | 0.98 (0.95–1.02) | 0.29 | 0.95 (0.92–0.99) | 0.02 | 1.04 (0.98–1.10) | 0.20 |
*Patients without second-line drug resistance who attended >2 visits. All analyses adjusted for no. of visits <1 y after diagnosis. Excludes 47 patients who are missing data on age, sex, or both. NA, not applicable; OR, odds ratio; RR, rifampin-resistant; TB, tuberculosis. †Estimated change per quarter (i.e., 3 mos).