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Experimental SARS-CoV-2 Infection of Bank Voles

Lorenz Ulrich¹, Anna Michelitsch¹, Nico Halwe¹, Kerstin Wernike, Donata Hoffmann, and Martin Beer

Author affiliation: Friedrich-Loeffler-Institut, Greifswald–Insel Riems, Germany

RT-qPCR results of the swap sampling of all inoculated and contact bank voles*

Box	Status	Swab	−1 dpi	2 dpi	4 dpi	8 dpi	12 dpi	16 dpi
Box 1	Inoculated	Oral	Neg	32.45	Neg	Neg	Neg	Neg
		Nasal	Neg	32.29	Neg	Neg	Neg	Neg
		Rectal	Neg	Neg	Neg	Neg	Neg	Neg
	Inoculated	Oral	Neg	NA	NA	NA	NA	NA
		Nasal	Neg	NA	NA	NA	NA	NA
		Rectal	Neg	NA	NA	NA	NA	NA
	Inoculated	Oral	Neg	32.09	28.16	Neg	Neg	Neg
		Nasal	Neg	31.72	34.03	Neg	Neg	Neg
		Rectal	Neg	36.54	36.39	Neg	Neg	Neg
	Contact	Oral	Neg	Neg	Neg	Neg	Neg	Neg
		Nasal	Neg	Neg	Neg	Neg	Neg	Neg
		Rectal	Neg	Neg	Neg	Neg	Neg	Neg
	Collected feces		Neg	36.58	37.66	Neg	Neg	Neg
Box 2	Inoculated	Oral	Neg	29.40	32.41	NA	NA	NA
		Nasal	Neg	32.68	34.72	NA	NA	NA
		Rectal	Neg	Neg	Neg	NA	NA	NA
	Inoculated	Oral	Neg	30.46	32.54	Neg	NA	NA
		Nasal	Neg	32.30	Neg	Neg	NA	NA
		Rectal	Neg	36.67	Neg	Neg	NA	NA
	Inoculated	Oral	Neg	32.72	37.07	Neg	Neg	Neg
		Nasal	Neg	34.74	Neg	Neg	Neg	Neg
		Rectal	Neg	Neg	Neg	Neg	Neg	Neg
	Contact	Oral	Neg	Neg	Neg	Neg	Neg	Neg
		Nasal	Neg	Neg	Neg	Neg	Neg	Neg
		Rectal	Neg	Neg	Neg	Neg	Neg	Neg
	Collected feces		Neg	36.06	36.65	Neg	Neg	Neg
Box 3	Inoculated	Oral	Neg	30.98	Neg	Neg	NA	NA
		Nasal	Neg	31.63	Neg	Neg	NA	NA
		Rectal	Neg	Neg	Neg	Neg	NA	NA
	Inoculated	Oral	Neg	30.66	34.32	NA	NA	NA
		Nasal	Neg	34.52	Neg	NA	NA	NA
		Rectal	Neg	Neg	34.89	NA	NA	NA
	Inoculated	Oral	Neg	32.64	Neg	Neg	Neg	NA
		Nasal	Neg	35.46	Neg	Neg	Neg	NA
		Rectal	Neg	Neg	Neg	Neg	Neg	NA
	Contact	Oral	Neg	Neg	Neg	Neg	Neg	Neg
		Nasal	Neg	Neg	Neg	Neg	Neg	Neg
		Rectal	Neg	Neg	Neg	Neg	Neg	Neg
	Collected feces		Neg	36.62	37.02	Neg	Neg	Neg

*Results are given in quantification cycle values. dpi, days postinoculation; NA, not applicable; Neg, negative.

Main Article

¹These authors contributed equally to this article.

Page created: January 25, 2021

Page updated: March 18, 2021

Page reviewed: March 18, 2021

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Volume 27, Number 4—April 2021

Research Letter

Experimental SARS-CoV-2 Infection of Bank Voles

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