Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 27, Number 6—June 2021
Research

Precision Tracing of Household Dengue Spread Using Inter- and Intra-Host Viral Variation Data, Kamphaeng Phet, Thailand

Irina Maljkovic Berry1Comments to Author , Melanie C. Melendrez1, Simon Pollett, Katherine Figueroa, Darunee Buddhari, Chonticha Klungthong, Ananda Nisalak2, Michael Panciera, Butsaya Thaisomboonsuk, Tao Li, Tyghe G. Vallard, Louis Macareo, In-Kyu Yoon, Stephen J. Thomas, Timothy Endy, and Richard G. Jarman
Author affiliations: Walter Reed Army Institute of Research Viral Diseases Branch, Silver Spring, Maryland, USA (I. Maljkovic Berry, M.C. Melendrez, S. Pollett, K. Figueroa, M. Panciera, T. Li, T.G. Vallard, R.G. Jarman); Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand (D. Buddhari, C. Klungthong, A. Nisalak, B. Thaisomboonsuk, L. Macareo); International Vaccine Institute, Seoul, South Korea (I.-K. Yoon); Upstate Medical University of New York Department of Medicine, Syracuse, New York, USA (S.J. Thomas, T. Endy)

Main Article

Table 1

Summary of probable household-to-household spread of dengue virus inferred by consensus genomes, Kamphaeng Phet, Thailand, 2009–2012

Serotype and sublineage Subdistrict Origin household† (location probability) Destination household (location probability) Approximate distance, m Sampling time difference, d
DENV-1, sublineage 1 LD LD02H075 (1.0) LD01H116 (1.0) 1,400 19
DENV-1, sublineage 1 SK SK06H346 (0.99) SK06H370 (1.0) 3,000 29
DENV-1, sublineage 7 TN TN18H021 (0.88) TN18H014 (1.0) 80 1
DENV-1, sublineage 7 NC NC06H057 (0.82) NC06H407 (1.0) 30 0, 14‡
DENV-2, sublineage 2 NB NB06H055 (0.80) NB06H084 (1.0) 800 13
DENV-2, sublineage 2 NP NP08H080 (0.82) NP08H044 (1.0) 180 0
DENV-2, sublineage 6 SK SK06H790 (0.99) SK06H485 (1.0) 3,000 49

*LD, Lan Dokmai; NB, Na Bo Kham; NC, Nakhon Chum; NP, Nong Pling; SK, Sa Kaeo; TN, Thep Nakhon.
†Households are described by their subdistrict, cluster, and house numbers, such that the first 2 letters denote subdistrict, the next 2-digit number denotes cluster, and an H followed by a 3-digit number denotes house number.
‡Two persons from the donor household were dengue virus–positive 2 weeks apart.‡

Main Article

1These authors contributed equally to this article.

2Deceased.

Page created: April 01, 2021
Page updated: May 18, 2021
Page reviewed: May 18, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external