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Volume 27, Number 7—July 2021
Research

Severe Acute Respiratory Syndrome Coronavirus 2 P.2 Lineage Associated with Reinfection Case, Brazil, June–October 2020

Paola Cristina ResendeComments to Author , João Felipe Bezerra, Romero Henrique Teixeira Vasconcelos, Ighor Arantes, Luciana Appolinario, Ana Carolina Mendonça, Anna Carolina Paixao, Ana Carolina Duarte, Thauane Silva, Alice Sampaio Rocha, Ana Beatriz Machado Lima, Alex Pauvolid-Corrêa, Fernando Couto Motta, Dalane Loudal Florentino Teixeira, Thiago Franco de Oliveira Carneiro, Francisco Paulo Freire Neto, Isabel Diniz Herbster, Anderson Brandao Leite, Irina Nastassja Riediger, Maria do Carmo Debur, Felipe Gomes Naveca, Walquiria Almeida, Mirian Livorati, Gonzalo Bello1, and Marilda M. Siqueira1
Author affiliations: Instituto Oswaldo Cruz, Rio de Janeiro, Brazil (P.C. Resende, I. Arantes, L. Appolinario, A.C. Mendonça, A.C. Paixao, A.C. Duarte, T. Silva, A.S. Rocha, A.B.M. Lima, A. Pauvolid-Corrêa, F.C. Motta, G. Bello, M.M. Siqueira); Universidade Federal da Paraíba, João Pessoa, Brazil (J.F. Bezerra, R.H.T. Vasconcelos); Texas A&M University, College Station, Texas, USA (A. Pauvolid-Corrêa); Laboratório Central do Estado da Paraíba, João Pessoa (L.F. Teixeira, T.F. de Oliveira Carneiro); Universidade Federal do Rio Grande do Norte, Natal, Brazil (F.P.F. Neto); Maternidade Escola Januario Cicco, Natal (I.D. Herbster); Laboratório Central do Estado do Alagoas, Maceió, Brazil (A.B. Leite); Laboratório Central do Estado do Paraná, Curitiba, Brazil (I.N. Riediger, M.C. Debur); Instituto Leônidas e Maria Deane, on behalf of the COVIDNORTE team, Manaus, Brazil (F.G. Naveca); Ministério da Saúde do Brasil, Brasilia, Brazil (W. Almeida, M. Livorati)

Main Article

Table

Laboratory test results of severe acute respiratory syndrome coronavirus 2 reinfection case-patient, Brazil, June–October 2020*

Clinical specimens Symptom onset Collection date RT-PCR SARS-CoV-2 RT-PCR SARS-CoV-2 (LVRS, Fiocruz) Sequencing
GISAID clade/PANGO lineage Antigen test (Abbott) IgG Neutralization assay
NPS, sample 1
 2020 Jun 17
 2020 Jun 23
 Positive, Ct E = 22, Ct RP = 21 (LACEN-PB)
 Positive, Ct E = 24, Ct N1 = 24, Ct N2 = 25, Ct RP = 26
 GR/B.1.1.33
 Positive
 NA
 NA
NPS, sample 2
 Asymptomatic
 2020 Sep 8
 ND, Ct E = ND, Ct RP = 25 (UFRN)
 NA
 NA
 NA
 NA
 NA
NPS, sample 3
 2020 Oct 11
 2020 Oct 13
 Positive, Ct E = 25, Ct RP = 24 (LACEN-PB)
 Positive, Ct E = 22, Ct N1 = 23, Ct N2 = 22, Ct RP = 26
 GR/P.2
 Positive
 NA
 NA
Serum specimen, sample 4 NA 2020 Dec 13 NA NA NA NA Positive B.1<10, P.1<10, P.2<10, B.1.1.7<10

*CPE, cytopathic effect; Ct, cycle threshold; E, envelope protein; LACEN-PB, Laboratório Central do Estado da Paraíba; LVRS, Respiratory Virus and Measles Laboratory; N1 and N2, portion of nucleoprotein; NA, not applicable; ND, not detected; NPS, nasopharyngeal swab specimen; PANGO, Phylogenetic Assignment of Named Global Outbreak Lineages; RP, human RNase P gene; RT-PCR, reverse transcription PCR; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; UFRN, Federal University of Rio Grande do Norte.

Main Article

1These authors share senior authorship.

Page created: April 12, 2021
Page updated: June 16, 2021
Page reviewed: June 16, 2021
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