Volume 27, Number 8—August 2021
Tuberculosis-Associated Hospitalizations and Deaths after COVID-19 Shelter-In-Place, San Francisco, California, USA
|Variable||Pre-SIP: 2019 Jan 1–2020 Mar 15||SIP: 2020 Mar 16–2021 Jan 30||p value†|
|New diagnoses of active TB||114 (100)||52 (100)‡||NA|
|Average no. new TB cases/month||7.9||5.0||NA|
|Median age of case-patients, y (range)||64.0 (3–101)||66.0 (15–97)||NS|
|New case-patients with cavitary TB||33 (28.9)||11 (21.2)||NS|
|New TB case-patients requiring hospitalization||38 (33.3)||33 (63.5)||0.0003|
|New TB case-patients requiring intensive care||5 (4.4)||12 (23.1)||0.0002|
|New TB case-patients who died||15 (13.2)||10 (19.2)||NS|
|New TB case-patients with TB-related deaths§||4 (3.5)||7 (13.5)||0.017|
*Values are no. (%) unless indicated. Cases were counted according to the month when TB was diagnosed. NA, not applicable; NS, not significant (p>0.05); SIP, shelter-in-place; TB, tuberculosis. †By Pearson χ2 test. ‡All patients were tested for severe acute respiratory syndrome coronavirus 2 co-infection at time of TB diagnosis, except for 7 patients for whom testing was not routinely available in the first 3 months of the pandemic (March–May 2020); no patients were positive. §Cause of death was evaluated by standardized algorithm and review of medical records and death certificate, when available. Deaths were counted as TB-related when TB was assessed as an immediate or contributing cause of death.
1These senior authors contributed equally to this article.