Volume 27, Number 9—September 2021
Research
Perinatal Outcomes of Asynchronous Influenza Vaccination, Ceará, Brazil, 2013–2018
Table 2
Characteristic | Value |
---|---|
Total SARI cases | 3,297 (100) |
Among pregnant women |
145 (4) |
Median age, y (range) |
25.95 (15–44) |
SARI cases with etiologic testing | 134 (100) |
Influenza | 43 (32) |
Noninfluenza | 11 (8) |
Unspecified or unknown | 80 (60) |
% Laboratory-confirmed influenza |
32.1 |
Influenza subtypes† | 43 (100) |
Seasonal A(H1N1) | 18 (42) |
Other seasonal A(H1) | 0 |
Seasonal A(H3) | 14 (33) |
A (unknown subtype) | 3 (7) |
B |
8 (19) |
SARI deaths‡ | 3 (100) |
Influenza | 0 |
Death rate of laboratory-certified influenza | 0 |
Other viruses/etiologic agents or unspecified | 3 (100) |
*Data from Notifiable Diseases Information System (19). Values are no. (%), except as indicated. SARI, severe acute respiratory infection. †Of total persons with identified influenza subtype. ‡Of total SARI deaths.
References
- World Health Organization. The top 10 causes of death. 2020 Dec 9 [cited 2021 Jul 7]. https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death
- Wang X, Li Y, O’Brien KL, Madhi SA, Widdowson MA, Byass P, et al.; Respiratory Virus Global Epidemiology Network. Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study. Lancet Glob Health. 2020;8:e497–510. DOIPubMedGoogle Scholar
- Schlaudecker EP, Steinhoff MC, Moore SR. Interactions of diarrhea, pneumonia, and malnutrition in childhood: recent evidence from developing countries. Curr Opin Infect Dis. 2011;24:496–502. DOIPubMedGoogle Scholar
- Simonsen L, Clarke MJ, Williamson GD, Stroup DF, Arden NH, Schonberger LB. The impact of influenza epidemics on mortality: introducing a severity index. Am J Public Health. 1997;87:1944–50. DOIPubMedGoogle Scholar
- Katz MA, Gessner BD, Johnson J, Skidmore B, Knight M, Bhat N, et al. Incidence of influenza virus infection among pregnant women: a systematic review. [Erratum in: BMC Pregnancy Childbirth. 2017;17:192]. BMC Pregnancy Childbirth. 2017;17:155. DOIPubMedGoogle Scholar
- Fell DB, Sprague AE, Liu N, Yasseen AS III, Wen SW, Smith G, et al.; Better Outcomes Registry & Network (BORN) Ontario. H1N1 influenza vaccination during pregnancy and fetal and neonatal outcomes. Am J Public Health. 2012;102:e33–40. DOIPubMedGoogle Scholar
- Regan AK, Feldman BS, Azziz-Baumgartner E, Naleway AL, Williams J, Wyant BE, et al. An international cohort study of birth outcomes associated with hospitalized acute respiratory infection during pregnancy. J Infect. 2020;81:48–56. DOIPubMedGoogle Scholar
- Dawood FS, Kittikraisak W, Patel A, Rentz Hunt D, Suntarattiwong P, Wesley MG, et al. Incidence of influenza during pregnancy and association with pregnancy and perinatal outcomes in three middle-income countries: a multisite prospective longitudinal cohort study. Lancet Infect Dis. 2021;21:97–106. DOIPubMedGoogle Scholar
- Mertz D, Geraci J, Winkup J, Gessner BD, Ortiz JR, Loeb M. Pregnancy as a risk factor for severe outcomes from influenza virus infection: A systematic review and meta-analysis of observational studies. Vaccine. 2017;35:521–8. DOIPubMedGoogle Scholar
- Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, et al.; Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: global and regional exposures and health consequences. Lancet. 2008;371:243–60. DOIPubMedGoogle Scholar
- Victora CG, Adair L, Fall C, Hallal PC, Martorell R, Richter L, et al.; Maternal and Child Undernutrition Study Group. Maternal and child undernutrition: consequences for adult health and human capital. Lancet. 2008;371:340–57. DOIPubMedGoogle Scholar
- Guerrant DI, Moore SR, Lima AAM, Patrick PD, Schorling JB, Guerrant RL. Association of early childhood diarrhea and cryptosporidiosis with impaired physical fitness and cognitive function four-seven years later in a poor urban community in northeast Brazil. Am J Trop Med Hyg. 1999;61:707–13. DOIPubMedGoogle Scholar
- MAL-ED Network Investigators. Early childhood cognitive development is affected by interactions among illness, diet, enteropathogens and the home environment: findings from the MAL-ED birth cohort study. BMJ Glob Health. 2018;3:
e000752 . DOIPubMedGoogle Scholar - Takeda S, Hisano M, Komano J, Yamamoto H, Sago H, Yamaguchi K. Influenza vaccination during pregnancy and its usefulness to mothers and their young infants. J Infect Chemother. 2015;21:238–46. DOIPubMedGoogle Scholar
- Almeida A, Codeço C, Luz PM. Seasonal dynamics of influenza in Brazil: the latitude effect. [Erratum in: BMC Infect Dis. 2018;19:225]. BMC Infect Dis. 2018;18:695. DOIPubMedGoogle Scholar
- Moura FEA, Perdigão ACB, Siqueira MM. Seasonality of influenza in the tropics: a distinct pattern in northeastern Brazil. Am J Trop Med Hyg. 2009;81:180–3. DOIPubMedGoogle Scholar
- Instituto Brasileiro de Geografia e Estatística. Fortaleza. 2017 [2021 July 7]. https://cidades.ibge.gov.br/brasil/ce/fortaleza/panorama
- Ministério da Saúde. Edict no. 1,271, June 6, 2014 [in Portuguese]. 2014 [2021 Jul 9]. https://bvsms.saude.gov.br/bvs/saudelegis/gm/2014/prt1271_06_06_2014.html
- Sistema de Informação de Agravos de Notificação. SINAN influenza. 2016 [cited 2021 Jul 7]. https://portalsinan.saude.gov.br/sinan-influenza
- World Health Organization. Global epidemiological surveillance standards for flu. 2014 [cited 2019 Dec 18]. https://apps.who.int/iris/handle/10665/311268
- Monto AS, Gravenstein S, Elliott M, Colopy M, Schweinle J. Clinical signs and symptoms predicting influenza infection. Arch Intern Med. 2000;160:3243–7. DOIPubMedGoogle Scholar
- Yang JH, Huang PY, Shie SS, Yang S, Tsao KC, Wu TL, et al. Predictive symptoms and signs of laboratory-confirmed influenza: a prospective surveillance study of two metropolitan areas in Taiwan. Medicine (Baltimore). 2015;94:
e1952 . DOIPubMedGoogle Scholar - World Health Organization. WHO information for the molecular detection of influenza viruses. 2017 [cited 2021 Jul 7]. https://www.who.int/influenza/gisrs_laboratory/WHO_information_for_the_molecular_detection_of_influenza_viruses_20171023_Final.pdf
- Global Health Data Exchange. Brazil live birth information system. 2018 [cited 2021 Jul 7]. http://ghdx.healthdata.org/series/brazil-live-birth-information-system-sinasc
- Kirkwood BR, Sterne JAC. Essential medical statistics. Malden (MA): Wiley-Blackwell; 2003.
- Tabachnick BG, Fidell LS. Using multivariate statistics. 6th ed. New York: Harper and Row; 2012.
- Simonsen L, Taylor R, Viboud C, Dushoff J, Miller M. US flu mortality estimates are based on solid science. BMJ. 2006;332:177–8. DOIPubMedGoogle Scholar
- Glezen WP, Keitel WA, Taber LH, Piedra PA, Clover RD, Couch RB. Age distribution of patients with medically-attended illnesses caused by sequential variants of influenza A/H1N1: comparison to age-specific infection rates, 1978-1989. Am J Epidemiol. 1991;133:296–304. DOIPubMedGoogle Scholar
- Bhat N, Wright JG, Broder KR, Murray EL, Greenberg ME, Glover MJ, et al.; Influenza Special Investigations Team. Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med. 2005;353:2559–67. DOIPubMedGoogle Scholar
- Omer SB, Goodman D, Steinhoff MC, Rochat R, Klugman KP, Stoll BJ, et al. Maternal influenza immunization and reduced likelihood of prematurity and small for gestational age births: a retrospective cohort study. PLoS Med. 2011;8:
e1000441 . DOIPubMedGoogle Scholar - Dodds L, MacDonald N, Scott J, Spencer A, Allen VM, McNeil S. The association between influenza vaccine in pregnancy and adverse neonatal outcomes. J Obstet Gynaecol Can. 2012;34:714–20. DOIPubMedGoogle Scholar
- Giles ML, Krishnaswamy S, Macartney K, Cheng A. The safety of inactivated influenza vaccines in pregnancy for birth outcomes: a systematic review. Hum Vaccin Immunother. 2019;15:687–99. DOIPubMedGoogle Scholar
- Niehaus MD, Moore SR, Patrick PD, Derr LL, Lorntz B, Lima AA, et al. Early childhood diarrhea is associated with diminished cognitive function 4 to 7 years later in children in a northeast Brazilian shantytown. Am J Trop Med Hyg. 2002;66:590–3. DOIPubMedGoogle Scholar
- Lorntz B, Soares AM, Moore SR, Pinkerton R, Gansneder B, Bovbjerg VE, et al. Early childhood diarrhea predicts impaired school performance. Pediatr Infect Dis J. 2006;25:513–20. DOIPubMedGoogle Scholar
- Governo do Estado do Ceará. Epidemiological Bulletin, Congenital Syndrome Associated with Zika Virus Infection [in Portuguese]. 2018 [cited 2021 Jul 7]. https://www.saude.ce.gov.br/wp-content/uploads/sites/9/2018/06/boletim_microcefalia_30_05_2018.pdf
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