Volume 27, Number 9—September 2021
Synopsis
Epidemiology, Clinical Features, and Outcomes of Coccidioidomycosis, Utah, 2006–2015
Adrienne Carey
, Morgan E. Gorris, Tom Chiller, Brendan Jackson, Wei Beadles, and Brandon J. Webb
, Morgan E. Gorris, Tom Chiller, Brendan Jackson, Wei Beadles, and Brandon J. Webb
Table 1
Demographic and clinical data from coccidioidomycosis cases identified in the Intermountain Healthcare system, Utah, USA, 2006–2015*
| Variables | No. (%) |
|---|---|
| Total patients |
364 |
| Demographics | |
| Age, y, median (IQR) | 61 (44–72) |
| Pediatric <18 y | 13 (3.6) |
| Male sex |
201 (55.2) |
| Race | |
| American Indian | 5 (1.4) |
| Asian | 2 (0.5) |
| Black | 1 (0.3) |
| Hispanic | 20 (5.5) |
| Pacific Islander | 9 (2.5) |
| Unknown | 7 (1.9) |
| White |
320 (87.9) |
| Coexisting conditions/medical factors | |
| Charlson comorbidity score, median (IQR) | 2 (0–4) |
| Diabetes mellitus | 81 (22.3) |
| Hepatic disease | 61 (16.8) |
| Chronic pulmonary disease | 144 (39.6) |
| Connective tissue disease | 27 (7.4) |
| Congestive heart failure | 53 (14.6) |
| Neurologic disease | 52 (14.3) |
| Renal disease | 45 (12.4) |
| History of malignancy | 76 (20.9) |
| Hematopoietic stem cell transplant | 2 (0.5) |
| Solid organ transplant | 2 (0.5) |
| Any immunosuppressive medication | 27 (7.4) |
| Corticosteroids | 25 (6.9) |
| Anti-TNF | 3 (0.8) |
| Antimetabolite | 2 (0.5) |
| Chemotherapy |
4 (1.1) |
| Laboratory test results | |
| Lymphopenia, absolute lymphocyte count <500 | 12 (3.3) |
| Lymphopenia value at diagnosis, absolute lymphocyte count, median (IQR) |
300 (300–400) |
| Outcomes | |
| Coccidioidomycosis-related hospital admission | 154 (42.3) |
| Hospital length of stay, d, median (IQR) | 0 (0–5) |
| 42-d all-cause mortality | 20 (5.5) |
| 1-y all-cause mortality |
33 (9.1) |
| Case classification | |
| Proven | 192 (52.7) |
| Probable | 172 (47.3) |
*Values are no. (%) except as indicated. IQR, interquartile range; TNF, tumor necrosis factor.
Page created: June 09, 2021
Page updated: August 17, 2021
Page reviewed: August 17, 2021
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