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Volume 28, Number 1—January 2022
Research

Global Genome Diversity and Recombination in Mycoplasma pneumoniae

Yu-Chia Hsieh, Shiao-Wen Li, Yi-Yin Chen, Ching-Chia Kuo, Yin-Cheng Chen, Ian Yi-Feng Chang, Yi-Jiun Pan, Ting-Hsuan Li, Ruei-Lin Chiang, Ya-Yu Huang, and Wei-Chao LiaoComments to Author 
Author affiliations: Chang Gung University, Taoyuan, Taiwan (Y.-C. Hsieh, S.-W. Li, Y.-C. Chen, I.Y.-.F. Chang, R.-L. Chiang, W.-C. Liao); Chang Gung Children's Hospital, Taoyuan (Y.-C. Hsieh, Y.-Y. Chen, C.-C. Kuo, T.-H. Li, Y.-Y. Huang); Linkou Chang Gung Memorial Hospital, Taoyuan (I.Y.-.F. Chang, W.-C. Liao); China Medical University, Taichung, Taiwan (Y.-J. Pan)

Main Article

Table

Putative recombination statistics for Mycoplasma pneumoniae clades for study of global genome diversity and recombination*

Clade No. strains Total SNPs No. SNPs inside recombination No. SNPs outside recombination No. recombination blocks r/m ρ/θ
T1–1 17 10.29 ± 23.44 5.65 ± 20.62 4.65 ± 6.78 0.18 ± 0.53 0.03 ± 0.14 0.01 ± 0.02
T1–2 146 9.78 ± 12.41 1.76 ± 4.06 8.02 ± 10.88 0.24 ± 0.55 0.25 ± 0.91 0.03 ± 0.12
T1–3 33 3.00 ± 5.70 0.18 ± 1.04 2.82 ± 5.53 0.03 ± 0.17 0.04 ± 0.21 0.01 ± 0.03
T2–2 46 14.46 ± 13.65 0.33 ± 1.71 14.13 ± 13.28 0.04 ± 0.21 0.02 ± 0.07 0 ± 0.01
T2–1 42 12.93 ± 16.71 1.98 ± 5.13 10.95 ± 12.59 0.26 ± 0.63 0.07 ± 0.17 0.01 ± 0.02

*Values are mean ± SD. r/m assesses the relative effect of recombination and mutation on genetic diversification of the clade. ρ/θ estimates the relative frequency of occurrence of recombination and mutation in the history of the clade. SNP, single-nucleotide polymorphism.

Main Article

Page created: September 02, 2021
Page updated: December 20, 2021
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