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Volume 28, Number 1—January 2022

Research

Streptococcus pneumoniae Serotypes Associated with Death, South Africa, 2012–2018

Annelies MüllerComments to Author , Jackie Kleynhans, Linda de Gouveia, Susan Meiring, Cheryl Cohen, Lucy Jane Hathaway1, Anne von Gottberg1, and for GERMS-SA
Author affiliations: University of Bern Graduate School for Cellular and Biomedical Sciences, Bern, Switzerland (A. Müller); University of Bern Institute for Infectious Diseases, Bern (A. Müller, L.J. Hathaway); National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa (J. Kleynhans, L. de Gouveia, S. Meiring, C. Cohen, A. von Gottberg); University of the Witwatersrand, Johannesburg (J. Kleynhans, S. Meiring, C. Cohen, A. von Gottberg); These authors contributed equally to this article.1

Main Article

Table 1

Demographic characteristics of patients with invasive pneumococcal disease, South Africa, 2012–2018*

Variable
 No. (%) patients
Total IPD cases, N = 4,272
 Total <15 y, n = 1,095
 Total >15 y, n = 3,177
Year of specimen collection
2012 792 (18.5) 237 (21.6) 555 (17.5)
2013 679 (15.99) 193 (17.6) 486 (15.3)
2014 601 (14.1) 194 (17.7) 407 (12.8)
2015 603 (14.1) 138 (12.6) 465 (14.6)
2016 585 (13.7) 136 (12.4) 449 (14.1)
2017 553 (12.9) 106 (9.7) 447 (14.1)
2018
 459 (10.7)
 91 (8.3)
 368 (11.6)
Province
Eastern Cape 272 (6.4) 55 (5.0) 217 (6.8)
Free State 221 (5.2) 83 (7.6) 138 (4.3)
Gauteng 1,636 (38.3) 417 (38.1) 1,219 (38.4)
KwaZulu-Natal 685 (16.0) 180 (16.4) 505 (15.9)
Limpopo 76 (1.8) 20 (1.9) 56 (1.8)
Mpumalanga 172 (4.0) 33 (3.0) 139 (4.4)
Northern Cape 214 (5.0) 36 (3.3) 178 (5.6)
North West 119 (2.8) 26 (2.4) 93 (2.9)
Western Cape
 877 (20.5)
 245 (22.4)
 632 (19.9)
Sex
F 2,184/4,267 (51.2) 505/1,093 (46.2) 1,679/3,174 (52.9)
M 2,083/4,267 (48.8) 588/1,093 (53.8) 1,495/3,174 (47.1)
Unknown
 5/4,272 (0.1)
 2/1,095 (0.2)
 3/1,095 (0.1)
Positive HIV status
 2,325/3,468 (67.0)
 318/905 (35.1)
 2,007/2,563 (78.3)
Age group
<1 y 504 (11.8) 504 (46.0) NA
1–4 y 319 (7.5) 319 (29.1) NA
5–14 y 272 (6.4) 272 (24.8) NA
15–24 y 282 (6.6) NA 282 (8.9)
25–44 y 1,738 (40.7) NA 1738 (54.7)
45–64 y 917 (21.5) NA 917 (28.9)
>65 y
 240 (5.6)
 NA
 240 (7.6)
Race
Black 3,452/4,160 (83.0) 939/1,066 (88.1) 2,513/3,094 (81.2)
All others 708/4,160 (17.0) 127/1,066 (11.9) 581/3,094 (18.8)

*Data from GERMS-SA (https://www.nicd.ac.za/germs) enhanced surveillance sites. NA, not applicable.

Main Article

Page created: December 13, 2021
Page updated: December 20, 2021
Page reviewed: December 20, 2021
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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