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Volume 28, Number 1—January 2022
Dispatch

SARS-CoV-2 RNA Shedding in Semen and Oligozoospermia of Patient with Severe Coronavirus Disease 11 Weeks after Infection

Lawrence J. PurpuraComments to Author , Joseph Alukal, Alexander M. Chong, Lihong Liu, Anyelina Cantos, Jayesh Shah, Nicola Medrano, Jennifer Y. Chang, Moriya Tsuji, Hiroshi Mohri, Anne Catrin Uhlemann, David Ho, and Michael T. Yin
Author affiliations: Columbia Mailman School of Public Health, New York, New York, USA (L.J. Purpura); Columbia University Irving Medical Center, New York (L.J. Purpura, J. Alukal, A.M. Chong, L. Liu, A. Cantos, J. Shah, N. Medrano, J.Y. Chang, M. Tsuji, H. Mohri, A.C. Uhlemann, D. Ho, M.T. Yin)

Main Article

Table 2

RT-PCR and serologic test results for participant 1 who was infected with SARS-CoV-2 in longitudinal prospective coronavirus disease cohort study, New York, USA*

Days after symptom onset Sample PCR result, Ct Binding antibody EC50, NP/S Neutralizing antibody IC50 T cell reactivity against M protein, IFN-γ‒secreting T cells/million PBMCs†
72 Saliva Negative
72
Blood
Negative
1,351/3,728 (modest)
(modest)

78
Saliva
Negative



78
Stool
Negative



78
Blood
Negative
1,756/5,680 (modest)
(modest)

81
Semen
Positive, 34.79



81
Blood
NT


>130 (strong)
81
Saliva
Negative



101
Semen
Negative



101
Saliva
Negative



101
Stool
Negative



169
Saliva
Negative



169 Stool Negative
169 Semen Negative

*Ct, cycle threshold; EC50, concentration half of the maximum effect; IC50, half-maximal inhibitory concentration; IFN, interferon; NP, nucleocapsid protein; NT, not tested; PBMCs, peripheral blood mononuclear cells; S, spike protein; SARS-CoV 2, severe acute respiratory syndrome coronavirus 2.

Main Article

Page created: October 01, 2021
Page updated: October 13, 2021
Page reviewed: October 13, 2021
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