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Volume 28, Number 10—October 2022

Two Cases of Lassa Fever Successfully Treated with Ribavirin and Adjunct Dexamethasone for Concomitant Infections

Sylvanus Okogbenin, Cyril Erameh, Joseph Okoeguale, Osahogie Edeawe, Esele Ekuaze, Kelly Iraoyah, John Agho, Mirjam Groger, Benno Kreuels, Lisa Oestereich, Femi O. Babatunde, Peter Akhideno, Stephan Günther, Michael Ramharter, and Till OmansenComments to Author 
Author affiliations: Irrua Specialist Teaching Hospital, Irrua, Nigeria (S. Okogbenin, C. Erameh, J. Okoeguale, O. Edeawe, E. Ekuaze, K. Iraoyah, J. Agho, F.O. Babatunde, P. Akhideno); Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany (M. Groger, B. Kreuels, M. Ramharter, L. Oestereich, S. Günther, T. Omansen); University Medical Center, Hamburg-Eppenforf, Germany (M. Groger, B. Kreuels, M. Ramharter, T. Omansen); German Center for Infection Research, Partner Sites Hamburg-Lübeck-Borstel-Riems, Germany (M. Groger, B. Kreuels, L. Oestereich, S. Günther, M. Ramharter, T. Omansen)

Main Article


Laboratory parameters of 2 patients in Nigeria at admission who had Lassa fever, were given ribavirin and dexamethasone, and showed favorable outcomes*

Parameter Patient A Patient B
Hemoglobin, g/dL 9.8 9.2
Packed cell volume, % 26.40 31.40
Erythrocytes, × 109 cells/L 3.04 3.77
Mean corpuscular volume, fL 88.5 83.3
Mean corpuscular hemoglobin, pg 32.2 24.4
Mean corpuscular hemoglobin concentration, g/dL 36.4 29.3
Red cell distribution width, % 29.2 27.4
Platelets/mm3 155,000 140,000
Mean platelet volume, fL 12.4 10.3
Platelet distribution width, % 28.1 27.4
Total leukocytes, x 109 cells/L 7,800 14,400
Neutrophils, % 66.40 NA
Lymphocytes, % 18.50 NA
Monocytes, % 12.40 NA
Eosinophils, % 2.40 NA
Basophils, %
Clinical chemistry
Creatinine, mg/dL 2.8 1.1
Urea, mg/dL 81 57
Bilirubin, mg/dL 0.8 0.6
Total protein, g/dL 6.8 7.8
Alanine aminotransferase, IU/L 6 11
Aspartate aminotransferase, IU/L
Sodium, mmol/L 136 NA
Potassium, mmol/L 5 NA

*NA, not available.

Main Article

Page created: August 24, 2022
Page updated: September 21, 2022
Page reviewed: September 21, 2022
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