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Volume 28, Number 12—December 2022
Research

National Monkeypox Surveillance, Central African Republic, 2001–2021

Camille Besombes, Festus Mbrenga, Laura Schaeffer, Christian Malaka, Ella Gonofio, Jordi Landier, Ulrich Vickos, Xavier Konamna, Benjamin Selekon, Joella Namsenei Dankpea, Cassandre Von Platen, Franck Gislain Houndjahoue, Daniel Sylver Ouaïmon, Alexandre Hassanin, Nicolas Berthet, Jean-Claude Manuguerra, Antoine Gessain, Arnaud Fontanet1Comments to Author , and Emmanuel Nakouné-Yandoko1
Author affiliations: Sorbonne Université, Paris, France (C. Besombes); Institut Pasteur, Paris (C. Besombes, L. Schaeffer, C. Von Platen, N. Berthet, J.-C. Manuguerra, A. Gessain, A. Fontanet); Institut Pasteur, Bangui, Central African Republic (F. Mbrenga, C. Malaka, E. Gonofio, X. Konamna, B. Selekon, J. Namsenei Dankpea, E. Nakouné Yandoko); Aix Marseille Université, Marseille, France (J. Landier); Centre Hospitalier Universitaire, Bangui (F.G. Houndjahoue, D.S. Ouaïmon); Sorbonne Université, Paris (A. Hassanin); Institut Pasteur of Shanghai, Shanghai, China (N. Berthet); Conservatoire National des Arts et Métiers, Paris (A. Fontanet)

Main Article

Table

Characteristics of 327 cases investigated during monkeypox national monkeypox surveillance, Central African Republic, 2001–2021*

Characteristics Confirmed cases, n = 99 Suspected cases, n = 61 No. contacts, n = 167 p value
Sex 0.6
F 51 (53.1) 37 (60.7) 90 (53.9)
M 45 (46.9) 24 (39.3) 77 (46.1)
Data missing
 3
 0
 0
Median age, y (IQR)
 15.5 (5.5–27)
 8 (2–23)
 27 (14–40)
 <0.001
Age group, y <0.001
0–9 33 (35.9) 30 (50.9) 23 (17)
10–19 17 (18.5) 9 (15.2) 18 (13.3)
20–29 22 (23.9) 11 (18.6) 30 (22.2)
>30 20 (21.7) 9 (15.3) 64 (47.4)
Missing data
 7
 2
 32
Born before 1980† 0.001
Y 3 (3.3) 4 (6.8) 28 (20.7)
N 89 (96.7) 55 (93.2) 107 (79.3)
Missing data
 7
 2
 32
Status/occupation 0.001
Child 37 (51.9) 26 (61.9) 5 (13.2)
Farmer 16 (22.2) 11 (28.2) 15 (39.5)
Hunter/fisherman 6 (8.3) 0 1 (2.6)
Healthcare worker 0 1 (2.4) 4 (10.5)
Mine worker 2 (2.8) 0 6 (15.8)
Market trader 2 (2.8) 2 (4.8) 0
Other 9 (12.5) 2 (4.7) 7 (18.4)
Missing data
 27
 19
 129
Reported contact with a human case 0.004
Y 44 (65.7) 28 (75.7) 36 (94.7)
N 23 (34.3) 9 (24.3) 2 (5.3)
Missing data
 32
 24
 129
Contact setting <0.001
Home 40 (95.2) 22 (81.5) 17 (56.7)
Elsewhere 2 (4.8) 5 (18.5) 13 (43.3)
Missing data
 57
 34
 137
Fever before rash 0.1
Y 51 (85) 29 (96.7) NA
N 9 (15) 1 (3.3) NA
Missing data
 39
 31
 NA
Diagnostic sample collected <0.001
Blood 45 (49.5) 53 (86.9) 46 (97.9)
Pus 32 (35.2) 5 (8.2) 0
Crust 14 (15.4) 3 (4.9) 1 (2.1)
Missing data 8 0 120

*Values indicate no. (%) of available data except as indicated. Number of cases missing data are indicated for each characteristic. NA, not applicable †Presumably persons born before 1980 were vaccinated against smallpox.

Main Article

1These senior authors contributed equally to this article.

Page created: October 10, 2022
Page updated: November 21, 2022
Page reviewed: November 21, 2022
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