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Volume 28, Number 12—December 2022

Research Letter

Severe Human Case of Zoonotic Infection with Swine-Origin Influenza A Virus, Denmark, 2021

Klara M. AndersenComments to Author , Lasse S. Vestergaard, Jakob N. Nissen, Sophie J. George, Pia Ryt-Hansen, Charlotte K. Hjulsager, Jesper S. Krog, Marianne N. Skov, Søren Alexandersen, Lars E. Larsen, and Ramona Trebbien
Author affiliations: Technical University of Denmark, Kongens Lyngby, Denmark (K.M. Andersen); Statens Serum Institut, Copenhagen, Denmark (K.M. Andersen, L.S. Vestergaard, J.N. Nissen, C.K. Hjulsager, J.S. Krog, S. Alexandersen, R. Trebbien); University of Copenhagen, Copenhagen (S.J. George, P. Ryt-Hansen, L.E. Larsen); Odense University Hospital, Odense, Denmark (M.N. Skov)

Main Article

Figure

Maximum-likelihood phylogenetic tree of the hemagglutinin gene of influenza A virus from a patient in Denmark (A/Denmark/36/2021), the seasonal vaccine strain, and closely related strains. The tree includes the case variant virus A/Denmark/36/2021 (red), the 10 closest BLAST matches (https://blast.ncbi.nlm.nih.gov/Blast.cgi), the previously reported Denmark variant virus A/Denmark/1/2021 (green), human seasonal reference viruses with >85% nucleotide identity to A/Denmark/36/2021 (Appendix 2 Table), and representative viruses from the passive surveillance program of influenza viruses in pigs from Denmark. The tree is rooted on A/California/07/2009. Human IAV sequences are shown in blue, and most seasonal reference viruses have been collapsed. Scale bar indicates nucleotide substitutions per site.

Figure. Maximum-likelihood phylogenetic tree of the hemagglutinin gene of influenza A virus from a patient in Denmark (A/Denmark/36/2021), the seasonal vaccine strain, and closely related strains. The tree includes the case variant virus A/Denmark/36/2021 (red), the 10 closest BLAST matches (https://blast.ncbi.nlm.nih.gov/Blast.cgi), the previously reported Denmark variant virus A/Denmark/1/2021 (green), human seasonal reference viruses with >85% nucleotide identity to A/Denmark/36/2021 (Appendix 2 Table), and representative viruses from the passive surveillance program of influenza viruses in pigs from Denmark. The tree is rooted on A/California/07/2009. Human IAV sequences are shown in blue, and most seasonal reference viruses have been collapsed. Scale bar indicates nucleotide substitutions per site.

Main Article

Page created: October 21, 2022
Page updated: November 21, 2022
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