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Volume 28, Number 3—March 2022

Overseas Treatment of Latent Tuberculosis Infection in US–Bound Immigrants

Amera KhanComments to Author , Christina R. Phares, Hoang Lan Phuong, Dang Thi Kieu Trinh, Ha Phan, Cindy Merrifield, Phan Thi Hong Le, Quach Thi Kim Lien, Sooc Ngoc Lan, Phan Thi Kim Thoa, Le Tran Minh Thu, Tiffany Tran, Cuc Tran, Lucy Platt, Susan A. Maloney, Nguyen Viet Nhung, Payam Nahid, and John E. Oeltmann
Author affiliations: Stop TB Partnership, Geneva, Switzerland (A. Khan); London School of Hygiene and Tropical Medicine, London, UK (A. Khan, L. Platt); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.R. Phares, C. Tran, S.A. Maloney, J.E. Oeltmann); Cho Ray Hospital Visa Medical Clinic, Ho Chi Minh City, Vietnam (H.L. Phuong, D.T.K. Trinh, P.T.H. Le, Q.T.K. Lien, S.N. Lan, P.T.K. Thoa, L.T.M. Thu); Vietnam National TB Program/University of California–San Francisco Research Collaboration, Hanoi, Vietnam (H. Phan, C. Merrifield, T. Tran, N.V. Nhung, P. Nahid); University of California–San Francisco, San Francisco, California, USA (H. Phan, C. Merrifield, P. Nahid); Vietnam National TB Program, Hanoi (N.V. Nhung)

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Table 3

Reasons IGRA not processed or 3HP not offered to participants in the Preventing Tuberculosis Overseas Pilot Study of US immigrant visa applicants, Vietnam, 2018–2019*

Reason No. (%) participants
IGRA not processed for participants who consented to be tested 162 (100)
Previous TB or abnormality on chest radiograph 119 (73)
Hepatitis B 25 (15)
History of extrapulmonary TB 3 (2)
Previous treatment 1 (1)
Breastfeeding 1 (1)
Applying for visa type not included in study 2 (1)
Recent receipt of live virus vaccine 1 (1)
Unknown; may have withdrawn consent
10 (7)
3HP not offered to IGRA-positive participants 32 (100)
Hepatitis B 18 (56)
Hepatitis C 5 (16)
Previous TB or abnormality on chest radiograph 1 (3)
Liver disease 1 (3)
Planning to get pregnant in next 4 mo 1 (3)
Substance addiction 1 (3)
Previous LTBI treatment 3 (9)
Unknown 2 (6)

*IGRA, interferon-γ release assay; LTBI, latent tuberculosis infection; TB, tuberculosis; 3HP, 3-mo regimen of isoniazid and rifapentine.

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Page created: December 13, 2021
Page updated: February 21, 2022
Page reviewed: February 21, 2022
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