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Volume 28, Number 5—May 2022
Research

Determining Existing Human Population Immunity as Part of Assessing Influenza Pandemic Risk

Jonathan Tin Lai Cheung, Tim K. Tsang, Hui-ling Yen, Ranawaka A.P.M. Perera, Chris Ka Pun Mok, Yong Ping Lin, Benjamin J. Cowling, and Malik PeirisComments to Author 
Author affiliations: University of Hong Kong, Hong Kong (J.T.L. Cheung, T.K. Tsang, H. Yen, R.A.P.M. Perera, C.K.P. Mok, B.J. Cowling, M. Peiris); Chinese University of Hong Kong, Hong Kong (C.K.P. Mok); First Affiliated Hospital of Guangzhou Medical University, Guangdong, China (Y.P. Lin)

Main Article

Table 2

Age-stratified seroprevalence and GMT to swine influenza viruses of different lineages among 353 persons in Hong Kong and Guangzhou, China*

Patient age, y NS4003 EA, H1N1
GD104 EA, H1N1
NS301 TRIG, H1N2
TS1436 H1N1pdm09
TS4348 BD-like H3N2
Sero† (%) GMT (95% CI) Sero† (%) GMT 
(95% CI) Sero† (%) GMT 
(95% CI) Sero† (%) GMT 
(95% CI) Sero† (%) GMT 
(95% CI)
<10
7/33
(21.2)
11
(7–16)

3/33
(9.1)
7
(5–9)

2/33
(6.1)
8
(6–10)

21/33
(63.6)
63
(34–119)

18/33
(54.5)
28
(15–51)
11–20
3/42
(7.1)
8
(6–9)

2/42
(4.8)
7
(5–9)

1/42
(2.4)
7
(6–8)

30/42
(71.4)
54
(36–81)

37/42
(88.1)
115
(81–162)
21–30
3/38
(7.8)
8
(6–10)

10/38
(26.3)
13
(8–19)

4/38
(10.5)
8
(6–10)

23/38
(60.5)
34
(22–52)

35/38
(92.1)
154
(106–225)
31–40
4/42
(9.5)
7
(6–9)

6/42
(14.3)
9
(7–12)

6/42
(14.3)
10
(8–14)

17/42
(40.5)
20
(13–29)

27/42
(64.3)
40
(27–59)
41–50
9/40
(22.5)
11
(8–15)

5/40
(12.5)
7
(5–10)

6/40
(15)
9
(7–13)

13/40
(32.5)
14
(10–21)

24/40
(60)
33
(23–48)
51–60
3/40
(7.5)
7
(5–10)

3/40
(7.5)
7
(5–9)

2/40
(5)
8
(6–11)

7/40
(17.5)
10
(7–15)

19/40
(47.5)
28
(18–42)
61–70
1/39
(2.5)
6
(5–7)

2/39
(5.1)
6
(5–8)

1/39
(2.6)
7
(6–8)

11/39
(28.2)
12
(8–17)

21/39
(53.8)
27
(19–38)
>70 4/79
(5.1)
7
(6–7)
8/79
(10.1)
8
(7–10)
5/79
(6.3)
7
(6–8)
24/79
(30.4)
15
(12–20)
58/79
(73.4)
54
(42–68)

*Serum samples were collected during 2013–2014 in Hong Kong and during 2015 in Guangzhou. BD, Binh Duong; EA, Eurasian–avian-like; GMT, geometric mean titer; sero, seroprevalence; TRIG, triple-reassortant internal gene. †Proportion of persons with hemagglutination inhibition antibody titers >1:40.

Main Article

Page created: February 24, 2022
Page updated: April 19, 2022
Page reviewed: April 19, 2022
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