Epidemiologic and Genomic Analysis of SARS-CoV-2 Delta Variant Superspreading Event in Nightclub, the Netherlands, June 2021
Jelle Koopsen
1![Comments to Author](/eid/content/images/icon/email.gif)
, Catharina E. van Ewijk
1, Roisin Bavalia, Akke Cornelissen, Sylvia M. Bruisten, Floor de Gee, Alvin X. Han, Maarten de Jong, Menno D. de Jong, Marcel Jonges, Norin Khawaja, Fleur M.H.P.A. Koene, Mariken van der Lubben, Iris Mikulic, Sjoerd P.H. Rebers, Colin A. Russell, Janke Schinkel, Anja J.M. Schreijer, Judith A. den Uil, Matthijs R.A. Welkers, Tjalling Leenstra, and
on behalf of the ARGOS consortium
Author affiliations: Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, the Netherlands (J. Koopsen, A.X. Han, M.D. de Jong, M. Jonges, S.P.H. Rebers, C.A. Russell, J. Schinkel, M.R.A. Welkers); Public Health Service Amsterdam, the Netherlands. (C.E. van Ewijk, R. Bavalia, A. Cornelissen, S.M. Bruisten, F. de Gee, M. de Jong, N. Khawaja, F.M.H.P.A. Koene, M. van der Lubben, I. Mikulic, A.J.M. Schreijer, J.A. den Uil, M.R.A. Welkers, T. Leenstra)
Main Article
Figure 2
![Detected increase of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequences with signature first detected in nightclub samples, Amsterdam, the Netherlands. A) Absolute number of weekly cases in randomly selected surveillance samples in the Amsterdam region, colored by the nucleotides at position 4321 and 22792 of the SARS-CoV-2 genome. B) Time-resolved phylogenetic tree of dataset containing all Netherlands SARS-CoV-2 Delta variant sequences available in GISAID on August 1, 2021, random surveillance samples from the Amsterdam region, and samples from returning travelers to the Amsterdam region. Tips are colored by the nucleotides at position 4321 and 22792 and epidemiologic linkage to the nightclub (with signature C4321T + 22792C). Dashed red line indicates the day of lifting 1.5-meter social distancing restrictions with QR code. NA, not applicable.](/eid/images/21-2019-F2.jpg)
Figure 2. Detected increase of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequences with signature first detected in nightclub samples, Amsterdam, the Netherlands. A) Absolute number of weekly cases in randomly selected surveillance samples in the Amsterdam region, colored by the nucleotides at position 4321 and 22792 of the SARS-CoV-2 genome. B) Time-resolved phylogenetic tree of dataset containing all Netherlands SARS-CoV-2 Delta variant sequences available in GISAID on August 1, 2021, random surveillance samples from the Amsterdam region, and samples from returning travelers to the Amsterdam region. Tips are colored by the nucleotides at position 4321 and 22792 and epidemiologic linkage to the nightclub (with signature C4321T + 22792C). Dashed red line indicates the day of lifting 1.5-meter social distancing restrictions with QR code. NA, not applicable.
Main Article
Page created: February 18, 2022
Page updated: April 19, 2022
Page reviewed: April 19, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.