Figure. Monthly cases of hospitalized, severe, and critical COVID-19 cases among women of childbearing age (15–42 years) and pregnant women at Nord Franche-Comté Hospital, France, March 1, 2020–November 15, 2021. We assessed COVID-19 disease severity against circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants during 3 periods of interest based on predominance of circulating variants. During period 1, wild-type virus comprised >50% of all sequenced SARS-CoV-2 variants in France; during period 2, >50% were Alpha variant; and during period 3, >50% were Delta variant. COVID-19, coronavirus disease; ICU, intensive care unit.