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Volume 28, Number 7—July 2022
Synopsis

Vaccine Effectiveness during Outbreak of COVID-19 Alpha (B.1.1.7) Variant in Men’s Correctional Facility, United States

Rachel A. Silverman1, Alessandro Ceci1, Alasdair Cohen, Meagan Helmick, Erica Short, Paige Bordwine, Michael J. Friedlander, and Carla V. FinkielsteinComments to Author 
Author affiliations: Virginia Tech, Blacksburg, Virginia, USA (R.A. Silverman, A. Cohen, M.J. Friedlander, C.V. Finkielstein); Fralin Biomedical Research Institute, Roanoke, Virginia, USA (A. Ceci, M.J. Friedlander, C.V. Finkielstein); Virginia Department of Health, Richmond, Virginia, USA (M. Helmick, E. Short, P. Bordwine).

Main Article

Figure 2

Raw (A) and normalized (B) Ct values for SARS-CoV-2 N, E, and S genes in samples collected from fully vaccinated and unvaccinated infected incarcerated persons during a facility outbreak, April 2021. The midline of the boxes represent the medians of the observations, the bottoms represents the first quartile, and the tops represent the third quartile; whiskers represent the minimum and maximum observations. In unadjusted linear regression comparing fully vaccinated to unvaccinated infected persons, only the E gene had statistically significantly different raw Ct values (p<0.05). All 3 genes had statistically significantly different normalized Ct values. Ct, cycle threshold; E, envelope gene; N, nucleocapsid gene; S, spike gene.

Figure 2. Raw (A) and normalized (B) Ct values for SARS-CoV-2 N, E, and S genes in samples collected from fully vaccinated and unvaccinated infected incarcerated persons during a facility outbreak, April 2021. The midline of the boxes represent the medians of the observations, the bottoms represents the first quartile, and the tops represent the third quartile; whiskers represent the minimum and maximum observations. In unadjusted linear regression comparing fully vaccinated to unvaccinated infected persons, only the E gene had statistically significantly different raw Ct values (p<0.05). All 3 genes had statistically significantly different normalized Ct values. Ct, cycle threshold; E, envelope gene; N, nucleocapsid gene; S, spike gene.

Main Article

1These authors contributed equally to this article.

Page created: May 21, 2022
Page updated: June 18, 2022
Page reviewed: June 18, 2022
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