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Volume 28, Number 8—August 2022
Research Letter

Invasive Streptococcus oralis Expressing Serotype 3 Pneumococcal Capsule, Japan

Bin ChangComments to Author , Masatomo Morita, Akiyoshi Nariai, Kei Kasahara, Akira Kakutani, Michinaga Ogawa, Makoto Ohnishi, and Kazunori Oishi
Author affiliations: National Institute of Infectious Diseases, Tokyo, Japan (B. Chang, M. Morita, M. Ogawa, M. Ohnishi); Matsue Red Cross Hospital, Shimane, Japan (A. Nariai); Nara Medical University, Nara, Japan (K. Kasahara); Nara City Hospital, Nara (A. Kakutani); Toyama Institute of Health, Toyama, Japan (K. Oishi)

Main Article


Characteristics of invasive Streptococcus oralis expressing serotype 3 pneumococcal capsule from 2 adult patients, Japan*

Case Onset date Isolate ID Source Positive Quellung reaction No. different bases
aroE gdh gki recP spi xpt ddl
1 January 2015 ASP0312-Sp Blood Pool R, serotype 3 61 30 44 32 4 41 37
2 April 2014 SP2752 Blood, CSF Pool R, serotype 3 54 –† 40 33 –† 47 36

*Each indicated allele from S. oralis isolates ASP0312-Sp and SP2752 was compared with corresponding alleles from S. pneumoniae that have been registered in the MLST database ( The number of different bases represents the number of polymorphisms between the isolates and the S. pneumoniae allele with the greatest homology. Pool R and pneumococcal serotype 3 antisera (Statens Serum Institut, CSF, cerebrospinal fluid; ID, identification; MLST, multilocus sequence typing; –, no different bases found. †The allele numbers were 341 for gdh and 406 for spi.

Main Article

1Current affiliation: Matsue Red Cross Hospital, Shimane, Japan.

Page created: June 03, 2022
Page updated: July 21, 2022
Page reviewed: July 21, 2022
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