Volume 28, Number 9—September 2022
Dispatch
Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus
Kaye Quizon, Kimberly Holloway, Mahmood Iranpour, Bryce M. Warner, Yvon Deschambault, Geoff Soule, Kevin Tierney, Darwyn Kobasa, Angela Sloan, and David Safronetz
Table
Summary of serologic analysis of serum samples from peromyscine rodents experimentally infected with Sin Nombre virus*
| Day | Sex | Peromyscus maniculatus rufinus | P. m. bairdii | P. m. sonoriensis | P. leucopus | P. polionotus | P. californicus |
|---|---|---|---|---|---|---|---|
| Day 21 | M | 2/3 | 0/3 | 1/3 | 3/4 | 3/3 | 0/3 |
| F | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 0/3 | |
| Total |
5/6 |
3/6 |
4/6 |
7/7 |
6/6 |
0/6 |
|
| Day 42 | M | 3/3 | 3/3 | 3/3 | 3/3 | 4/4 | 1/3 |
| F | 3/3 | 3/3 | 3/3 | 2/3 | 3/3 | 0/3 | |
| Total | 6/6 | 6/6 | 6/6 | 5/6 | 7/7 | 1/6 |
*Results shown are the number of seropositive animals per timepoint. Serum samples were tested by using a recombinant Sin Nombre orthohantavirus nucleocapsid-based ELISA for reactive antibodies that used a P. leucopus IgG heavy- and light-chain secondary antibody. Titers of >100 were considered positive.
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