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Volume 29, Number 1—January 2023

CME ACTIVITY - Synopsis

Comprehensive Review of Emergence and Virology of Tickborne Bourbon Virus in the United States

Molly K. Roe1, Elise R. Huffman1, Yara S. Batista, George G. Papadeas, Sydney R. Kastelitz, Anna M. Restivo, and Christopher C. StobartComments to Author 
Author affiliation: Butler University, Indianapolis, Indiana, USA (

Main Article

Figure 3

Geographic range of BRBV and its vector, the Amblyomma americanum tick. Confirmed human cases of BRBV infection and virus detection in nonhuman animals are superimposed over historic and expanded geographic ranges of the lone star tick (A. americanum). Confirmed human cases of BRBV infection were identified by the US Centers for Disease Control and Prevention, and detection of virus in nonhuman animals occurred primarily through sampling of ticks and subsequent testing by using PCR and serologic testing of mammals. BRBV, Bourbon virus.

Figure 3. Geographic range of BRBV and its vector, the Amblyomma americanum tick. Confirmed human cases of BRBV infection and virus detection in nonhuman animals are superimposed over historic and expanded geographic ranges of the lone star tick (A. americanum). Confirmed human cases of BRBV infection were identified by the US Centers for Disease Control and Prevention, and detection of virus in nonhuman animals occurred primarily through sampling of ticks and subsequent testing by using PCR and serologic testing of mammals. BRBV, Bourbon virus.

Main Article

1These first authors contributed equally to this article.

Page created: November 02, 2022
Page updated: December 21, 2022
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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