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Volume 29, Number 1—January 2023

Human Immunity and Susceptibility to Influenza A(H3) Viruses of Avian, Equine, and Swine Origin

Elien Vandoorn, Wojciech Stadejek, Isabel Leroux-Roels, Geert Leroux-Roels, Anna Parys, and Kristien Van ReethComments to Author 
Author affiliations: Ghent University, Merelbeke, Belgium (E. Vandoorn, W. Stadejek, A. Parys, K. Van Reeth); Ghent University and Ghent University Hospital, Ghent, Belgium (I. Leroux-Roels, G. Leroux-Roels)

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Table 3

Percentage amino acid homology (lower left) and number of identical amino acids out of 40 aa in presumed antigenic sites (upper right) (34) between hemagglutinin 1 of the H3 influenza A viruses used for study of human immunity and susceptibility to influenza A(H3) viruses of avian, equine, and swine origin*

Virus strain Avian
Eurasian American Eurasian Eurasian FC1 Pandemic European N. Am. N. Am.
dkUK63 37 36 36 24 33 22 20 18
mlOH18 93.9 39 37 25 34 22 18 18
mlBE18 96.7 95.1 38 26 34 21 18 17







swG17 81.4 81.1 82.1 80.8 77.9 83.4 22 22
swIN16 80.8 78.7 80.8 80.8 73.2 81.4 79.4 26
swMO15 79.6 77.5 79.0 77.8 71.4 79.9 79.2 82.9

*Viruses are ordered according to host species and chronologically according to the emergence of each of the influenza A virus lineages in these species. Blank cells indicate crossover points between comparisons. Complete isolate names are provided in [[ANCHOR###T2###Table 2###Anchor]]. FC1, Florida clade 1; N. Am., North American. †Human influenza A virus that no longer circulates.

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