Volume 29, Number 1—January 2023
Research
Human Immunity and Susceptibility to Influenza A(H3) Viruses of Avian, Equine, and Swine Origin
Elien Vandoorn, Wojciech Stadejek, Isabel Leroux-Roels, Geert Leroux-Roels, Anna Parys, and Kristien Van Reeth
Table 5
Geometric mean of virus neutralization antibody titers against H3 influenza A viruses of different species in different age groups of the human population, 2017–2018, Belgium*
| Birth year range (age, y)† |
No. | Avian |
Equine |
Human |
Swine |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dkUK63 |
mlOH18 |
mlBE18 |
chG19 |
eqCH18 |
HK68‡ |
swG17 |
swIN16 |
swMO15 |
|||||
| Eurasian | Am. | Eurasian | Eurasian | FC1 | Pandemic | European | N. Am. | N. Am. | |||||
| 1921–1926 (96–91) | 14 | 7 (5–9) | 10 (7–15) | 8 (6–12) | 6 (5–7) | 7 (5–10) | 30 (12–72) | 10 (5–19) | 104 (44–247) | 116 (38–351) | |||
| 1927–1936 (90–81) | 30 | 6 (5–7) | 12 (9–18) | 12 (8–17) | 6 (5–7) | 7 (5–8) | 43 (27–68) | 9 (6–11) | 60 (34–106) | 105 (62–176) | |||
| 1937–1946 (80–71) | 30 | 5 (5–6) | 9 (7–12) | 10 (7–14) | 5 (5–6) | 6 (5–6) | 48 (32–72) | 9 (6–12) | 33 (21–53) | 79 (46–137) | |||
| 1947–1956 (70–61) | 30 | 7 (5–9) | 14 (10–21) | 15 (11–22) | 6 (5–7) | 7 (5–9) | 69 (44–110) | 8 (6–11) | 31 (18–52) | 35 (20–60) | |||
| 1957–1966 (60–51) | 30 | 6 (5–7) | 15 (11–20) | 19 (13–27) | 7 (5–9) | 6 (5–6) | 100 (72–138) | 12 (8–16) | 28 (17–47) | 37 (24–56) | |||
| 1967–1976 (50–41) | 30 | 7 (5–9) | 11 (8–17) | 12 (8–17) | 6 (5–7) | 6 (5–7) | 31 (17–55) | 18 (13–25) | 94 (56–157) | 60 (35–103) | |||
| 1977–1986 (40–31) | 30 | 6 (5–7) | 7 (6–8) | 6 (5–7) | 5 (5–6) | 8 (6–10) | 9 (6–13) | 9 (7–12) | 285 (175–462) | 84 (45–154) | |||
| 1987–1996 (30–21) | 30 | 5 (5–5) | 6 (5–6) | 5 (5–6) | 5 (5–5) | 6 (5–7) | 6 (5–6) | 7 (6–8) | 219 (129–372) | 225 (156–323) | |||
| 1997–2006 (20–11) | 30 | 5 (5–5) | 5 (5–5) | 5 (5–5) | 5 (5–5) | 5 (5–6) | 5 (5–6) | 6 (5–7) | 18 (11–29) | 163 (96–275) | |||
| 2007–2017 (10–0) |
32 |
5 (5–5) |
5 (5–5) |
5 (5–5) |
5 (5–5) |
6 (5–7) |
6 (5–7) |
6 (5–6) |
8 (6–10) |
40 (24–67) |
|||
| 1921–2017 (96–0) | 286 | 6 (5–6) | 9 (8–10) | 9 (8–10) | 6 (5–6) | 6 (6–7) | 21 (18–25) | 9 (8–9) | 49 (40–60) | 77 (64–91) | |||
*Values represent geometric mean virus neutralization titers (95% CI). Viruses are ordered according to host species and chronologically according to the emergence of each of the influenza A virus lineages in these species. Complete isolate names are provided in [[ANCHOR###T2###Table 2###Anchor]]. Am., American; FC1, Florida clade 1; N. Am., North American. †Age at the end of 2017. ‡Human influenza A virus that no longer circulates.
Page created: November 30, 2022
Page updated: December 21, 2022
Page reviewed: December 21, 2022
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.