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Volume 29, Number 1—January 2023
Dispatch

COVID-19 Symptoms by Variant Period in the North Carolina COVID-19 Community Research Partnership, North Carolina, USA

Michael E. DeWittComments to Author , Ashley H. Tjaden, David Herrington, John Schieffelin, Michael Gibbs, William S. Weintraub, John W. Sanders1, Sharon L. Edelstein1, and on behalf of the COVID-19 Community Research Partnership
Author affiliations: Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA (M.E. DeWitt, D. Herrington, J.W. Sanders); The George Washington University Milken Institute of Public Health, Rockville, Maryland, USA (A.H. Tjaden, S.L. Edelstein); Tulane School of Medicine, New Orleans, Louisiana, USA (J.S. Schieffelin); Atrium Health, Charlotte, North Carolina, USA (M.A. Gibbs); MedStar Health, Columbia, Maryland, USA (W.S. Weintraub); Georgetown University, Washington, DC, USA (W.S. Weintraub)

Main Article

Table 2

Symptom duration among participants reporting symptoms by variant wave in study of COVID-19 infection, North Carolina, USA*

Variant period Beta (95% CI)† p value Marginal mean duration, d (95% CI)‡
Pre-Delta NA NA 9.7 (9.0–10.4)
Delta −1.3 (−2.0 to −0.57) <0.001 8.4 (7.8–9.1)
Omicron −3.8 (−4.6 to −3.1) <0.001 5.9 (5.3–6.4)

*Data are adjusted for age, vaccination status, boosting, reinfection, and sex. NA, not applicable. †Differences from reference wave (pre-Delta) in the linear model. ‡Marginal mean represents the estimated mean duration of a symptomatic period across all levels of age, vaccination status, boosting, reinfection, and sex.

Main Article

1These senior authors contributed equally to this article.

Page created: December 09, 2022
Page updated: December 22, 2022
Page reviewed: December 22, 2022
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