Efficient Inactivation of Monkeypox Virus by World Health Organization‒Recommended Hand Rub Formulations and Alcohols
Toni L. Meister, Ronny Tao, Yannick Brüggemann, Daniel Todt, Joerg Steinmann, Joerg Timm, Ingo Drexler, and Eike Steinmann
Author affiliations: Ruhr University Bochum, Bochum, Germany (T.L. Meister, Y. Brüggemann, D. Todt, E. Steinmann); Heinrich-Heine-University, Düsseldorf, Germany (R. Tao, J. Timm, I. Drexler); European Virus Bioinformatics Center, Jena, Germany (D. Todt); Paracelsus Medical University, Nuremberg, Germany (J. Steinmann); University Hospital of Essen, Essen, Germany (J. Steinmann)
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Figure 2
Figure 2. Effect of commercially available alcohols in inactivating monkeypox virus. A) Results for ethanol. B) Results for 2-propanol. Means of 3 independent experiments with SDs (error bars) are shown. Reduction factors are included above the bars. Biocide concentrations ranged from 0% to 80% with an exposure time of 30 s. Viral titers are displayed as TCID50/mL values. LLOQ, lower limit of quantification (1.58 × 102 TCID50/mL); NA, not applicable; TCID50, 50% tissue culture infectious dose; ULOQ, upper limit of quantification (1.58 × 109 TCID50/mL).
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