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Volume 29, Number 3—March 2023
Dispatch

Nosocomial Severe Fever with Thrombocytopenia Syndrome in Companion Animals, Japan, 2022

Hirohisa Mekata, Kazumi Umeki, Kentaro Yamada, Kunihiko Umekita, and Tamaki OkabayashiComments to Author 
Author affiliations: University of Miyazaki, Miyazaki, Japan (H. Mekata, K. Yamada, K. Umekita, T. Okabayashi); Kyushu University of Health and Welfare, Nobeoka, Japan (K. Umeki); University of Miyazaki Hospital, Miyazaki (K. Umekita)

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Table

Hematologic results and outcomes for 3 companion animals with severe fever with thrombocytopenia syndrome virus infection, Japan, 2022*

Characteristic Reference ranges†
 Dog 1
 Cat 1
 Cat 2
Canine Feline Jan 8 Jan 12 Jan 21 Jan 21
Real-time RT-PCR, copies/mL NA 1.99 × 106‡ ND§ 1.53 × 106 6.37 × 106
Virus isolation NA ND ND + +
ELISA (absorbance at 405 nm)
 (<0.04)§
ND
 ND
+ (0.39)
+ (2.92)
Temperature, °C 38.0–39.0 38.0–39.0 39.9 ND 37.2¶ 39.8
Leukocytes, × 102 cells/mL 40–155 30–148 81.0 49.4 13.1 73.7
Hemoglobin, g/dL 12.1–20.3 9.3–15.9 14.4 11.4 15.1 35.1
Platelets, × 104/mL 17–40 20–50 10.6 1.4 0.9 6.4
Total bilirubin, mg/dL 0.1–0.3 0.1–0.4 0.2 3.2 5.5 5.1
Alanine transaminase, U/L 12–118 10–100 157 189 566 148
Alkaline phosphatase, U/L 5–131 10–50 >1225 >1225 <10 16
Creatinine, mg/dL
 0.5–1.6
 0.6–2.4
0.8
 5.1
1.3
1.5
Outcome Euthanasia
 Death Recovery

*NA, not applicable; ND, not done; RT-PCR, reverse transcription PCR. †Standard canine and feline hematology parameters were selected according to (7). ‡Poorly preserved blood was used for real-time RT-PCR and virus isolation. §Cutoff value selected according to (8). ¶Temperature was 40.8°C on January 19.

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References
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Page created: January 22, 2023
Page updated: February 20, 2023
Page reviewed: February 20, 2023
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