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Volume 29, Number 4—April 2023
Synopsis

Association of Scrub Typhus in Children with Acute Encephalitis Syndrome and Meningoencephalitis, Southern India

Tina DamodarComments to Author , Bhagteshwar Singh, Namratha Prabhu1, Srilatha Marate1, Vykuntaraju K. Gowda, A.V. Lalitha, Fulton Sebastian Dsouza, Sushma Veeranna Sajjan, Mallesh Kariyappa, Uddhava V. Kinhal, P.V. Prathyusha, Anita Desai, Kandavel Thennarasu, Tom Solomon, Vasanthapuram Ravi, and Ravi YadavComments to Author 
Author affiliations: National Institute of Mental Health and Neurosciences, Bangalore, India (T. Damodar, N. Prabhu, S. Marate, P.V. Prathyusha, A. Desai, K. Thennarasu, V. Ravi, R. Yadav); Christian Medical College, Vellore, India (B. Singh); University of Liverpool, Liverpool, UK (B. Singh, T. Solomon); Liverpool University Hospitals NHS Foundation Trust, Liverpool (B. Singh, T. Solomon); Indira Gandhi Institute of Child Health, Bangalore (V.K. Gowda, U.V. Kinhal); St. John’s Medical College and Hospital, Bangalore (A.V. Lalitha, F.S. Dsouza); Vani Vilas Women and Children’s Hospital, Bangalore Medical College and Research Institute, Bangalore (S.V. Sajjan, M. Kariyappa); The Walton Centre NHS Foundation Trust, Liverpool (T. Solomon); The Pandemic Institute, Liverpool (T. Solomon)

Main Article

Table 1

Diagnostic criteria for certainty in the association of AES with scrub typhus in children, southern India*

Association of AES with scrub typhus Real-time PCR Serum IgM ELISA CSF IgM ELISA Simultaneous evidence of another pathogen(s)
Confirmed + +/− +/− +/−
Probable, single† – + +/− –
Probable, co-positive‡ – + + +
Possible – + – +

*AES, acute encephalitis syndrome; CSF, cerebrospinal fluid. †Without evidence of another potentially causative pathogen. ‡With evidence of another potentially causative pathogen.

Main Article

1These authors contributed equally to this article.

Page created: March 01, 2023
Page updated: March 21, 2023
Page reviewed: March 21, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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