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Volume 29, Number 4—April 2023
Research Letter

Blackwater Fever Treated with Steroids in Nonimmune Patient, Italy

Anna Rita Di Biase, Dora Buonfrate, Francesca Stefanelli, Giorgio Zavarise, Erica Franceschini, Cristina Mussini, Lorenzo Iughetti, and Federico GobbiComments to Author 
Author affiliations: University of Modena and Reggio Emilia, Modena, Italy (A.R. Di Biase, F. Stefanelli, C. Mussini, L. Iughetti); IRCCS Sacro Cuore don Calabria Hospital, Negrar, Verona, Italy (D. Buonfrate, G. Zavarise, F. Gobbi); Azienda Ospedaliero-Universitaria of Modena, Modena (E. Franceschini)

Main Article

Table

Laboratory exams during hospitalization for a 12-year-old girl with blackwater fever, Modena, Italy*

Parameter Day 1 Day 2 Day 4 Day 7 Day 10 Day 13 Day 23 Follow-up
Labwork
Hemoglobin, g/dL 12.3 9.1 7.8 10.2 7.9 9.9 10.1 12.6
Platelets, 103/mmc 27 45 96 79 354 379 451 301
Bilirubin, mg/dL 1.96 1.53 1.21 1.06 1.57 2.25 0.61 0.42
ALT, U/L 77 79 389 446 260 124 62 12
AST, U/L NA NA 1398 1435 254 128 35 NA
LDH, U/L 1870 1732 7676 7200 5147 5646 1715 513
PCR, mg/dL 23.8 15.2 24.3 11.6 1.5 1.8 <0.2 <0.2
Hemoglobinuria
N
N
Y
Y
Y
Y
N
N
Treatment
Artesunate × ×
Artemether/lumefantrine ׆
Blood transfusion × ×‡
Steroids ק

*ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; N, no; NA, not applicable; PCR, polymerase chain reaction; Y, yes; ×, administered; –, not administered. †Days 3–5. ‡Days 10, 12 and 16. §Days 13–17.

Main Article

Page created: March 01, 2023
Page updated: March 21, 2023
Page reviewed: March 21, 2023
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