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Volume 29, Number 5—May 2023
Research

Use of High-Resolution Geospatial and Genomic Data to Characterize Recent Tuberculosis Transmission, Botswana

Chelsea R. Baker1, Ivan Barilar1, Leonardo S. de Araujo, Anne W. Rimoin, Daniel M. Parker, Rosanna Boyd, James L. Tobias, Patrick K. Moonan, Eleanor S. Click, Alyssa Finlay, John E. Oeltmann, Vladimir N. Minin, Chawangwa Modongo, Nicola M. Zetola2, Stefan Niemann2, and Sanghyuk S. Shin2Comments to Author 
Author affiliations: University of California, Irvine, California, USA (C.R. Baker, D.M. Parker, V.N. Minin, S.S. Shin); Forschungszentrum, Borstel, Germany (I. Barilar, L.S. de Araujo, S. Niemann); University of California, Los Angeles, California, USA (A.W. Rimoin); US Centers for Disease Control and Prevention, Gaborone, Botswana (R. Boyd, A. Finlay); US Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.L. Tobias, P.K. Moonan, R. Boyd, E.S. Click, A. Finlay, J.E. Oeltmann); Botswana–UPenn Partnership, Gaborone (C. Modongo, N.M. Zetola); Victus Global Botswana Organisation, Gaborone (C. Modongo, N.M. Zetola)

Main Article

Figure 4

K-function differences for Mycobacterium tuberculosis genotypic groups A–E (≤5 single-nucleotide polymorphisms) compared with ungrouped strains in study of high-resolution geospatial and genomic data to characterize recent tuberculosis transmission, Gaborone, Botswana, 2012–2016. Differences in K-functions were used to assess geospatial clustering among participants in each group relative to participants with ungrouped strains. Observations falling above the upper 95% envelope indicate significant spatial clustering.

Figure 4. K-function differences for Mycobacterium tuberculosis genotypic groups A–E (≤5 single-nucleotide polymorphisms) compared with ungrouped strains in study of high-resolution geospatial and genomic data to characterize recent tuberculosis transmission, Gaborone, Botswana, 2012–2016. Differences in K-functions were used to assess geospatial clustering among participants in each group relative to participants with ungrouped strains. Observations falling above the upper 95% envelope indicate significant spatial clustering.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: January 18, 2023
Page updated: April 18, 2023
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