Skip directly to page options Skip directly to A-Z link
Volume 29, Number 5—May 2023
Dispatch

Rustrela Virus as Putative Cause of Nonsuppurative Meningoencephalitis in Lions

Madeleine de le Roi, Christina Puff, Peter Wohlsein, Florian Pfaff, Martin Beer, Wolfgang Baumgärtner, and Dennis RubbenstrothComments to Author 
Author affiliations: University of Veterinary Medicine Hannover Foundation, Hannover, Germany (M. de le Roi, C. Puff, P. Wohlsein, W. Baumgärtner); Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany (F. Pfaff, M. Beer, D. Rubbenstroth)

Main Article

Figure 2

Phylogenetic analysis and spatial distribution of rustrela virus infections in Europe. A) Maximum-likelihood phylogenetic tree of partial rustrela virus (RusV) sequences (409 nt, representing genome positions 100–508 of donkey-derived RusV reference genome, GenBank accession no. MN552442.2). Only bootstrap values at major branches are shown in the phylogenetic tree. RusV sequence names are shown in the format host/ISO 1366 code of location (federal, state, country)/animal ID/year. The tree was produced using IQ-TREE version 2.2.0; transition model 2 plus empirical frequency plus gamma 4 with 1,000 bootstrap replicates. Bold text indicates sequences from this study. Scale bar indicates substitutions per site. B) Mapping of the geographic origin of RusV-positive animals in Europe. Colors represent the phylogenetic clades of the sequences. Diamonds represent lions; circles, domestic cats; triangles, other zoo animals; squares, Apodemus spp. rodents. Symbols in gray boxes represent individuals from the same or very close locations. AUT, Austria; BE, Berlin; DEU/GER, Germany; MV, Mecklenburg–Western Pomerania; NI, Lower Saxony; NW, North Rhine–Westphalia; SWE, Sweden.

Figure 2. Phylogenetic analysis and spatial distribution of rustrela virus infections in Europe. A) Maximum-likelihood phylogenetic tree of partial rustrela virus (RusV) sequences (409 nt, representing genome positions 100–508 of donkey-derived RusV reference genome, GenBank accession no. MN552442.2). Only bootstrap values at major branches are shown in the phylogenetic tree. RusV sequence names are shown in the format host/ISO 1366 code of location (federal, state, country)/animal ID/year. The tree was produced using IQ-TREE version 2.2.0; transition model 2 plus empirical frequency plus gamma 4 with 1,000 bootstrap replicates. Bold text indicates sequences from this study. Scale bar indicates substitutions per site. B) Mapping of the geographic origin of RusV-positive animals in Europe. Colors represent the phylogenetic clades of the sequences. Diamonds represent lions; circles, domestic cats; triangles, other zoo animals; squares, Apodemus spp. rodents. Symbols in gray boxes represent individuals from the same or very close locations. AUT, Austria; BE, Berlin; DEU/GER, Germany; MV, Mecklenburg–Western Pomerania; NI, Lower Saxony; NW, North Rhine–Westphalia; SWE, Sweden.

Download

Main Article

Page created: April 04, 2023
Page updated: April 19, 2023
Page reviewed: April 19, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external