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Volume 29, Number 7—July 2023
Synopsis

Nationwide Outbreak of Candida auris Infections Driven by COVID-19 Hospitalizations, Israel, 2021–20221

Roni Biran, Regev Cohen, Talya Finn, Tal Brosh-Nissimov, Galia Rahav, Dafna Yahav, Sharon Amit, Yael Shachor-Meyouhas, Alaa Atamna, Jihad Bishara, Liat Ashkenazi-Hoffnung, Haim Ben Zvi, Mirit Hershman-Sarafov, Shlomo Maayan, Yasmin Maor, Orna Schwartz, Oren Zimhony, Jonathan Lellouche, Meital Elbaz, Ela Burdelova, Naama Mizrahi, Anna Novikov, Oryan Henig, and Ronen Ben-AmiComments to Author 
Author affiliations: Tel Aviv Sourasky Medical Center, Tel Aviv, Israel (R. Biran, M. Elbaz, E. Burdelova, N. Mizrahi, A. Novikov, O. Henig, R. Ben-Ami); Hillel Yaffe Medical Center, Hadera, Israel (R. Cohen); Technion, Haifa, Israel (R. Cohen, Y. Shachor-Meyouhas, M. Hershman-Sarafov); Sanz Medical Center, Netanya, Israel (T. Finn, J. Lellouche); Samson Assuta Ashdod University Hospital, Ashdod, Israel (T. Brosh-Nissimov); Ben Gurion University in the Negev, Beer Sheba, Israel (T. Brosh-Nissimov); Sheba Medical Center, Tel Hashomer, Israel (G. Rahav, D. Yahav, S. Amit); Tel Aviv University, Tel Aviv (G. Rahav, D. Yahav, A. Atamna, J. Bishara, L. Ashkenazi-Hoffnung, H. Ben Zvi, Y. Maor, R. Ben-Ami); Rambam Medical Center, Haifa (Y. Shachor-Meyouhas); Beilinson Hospital, Rabin Medical Center, Petach-Tikva, Israel (A. Atamna, J. Bishara); Schneider Children’s Medical Center, Petach-Tikva (L. Ashkenazi-Hoffnung); Bnai Zion Medical Center, Haifa (M. Hershman Sarafov); Barzilai Medical Center, Ashdod (S. Maayan); Hebrew University of Jerusalem, Jerusalem, Israel (S. Maayan, O. Zimhony); Wolfson Medical Center, Holon, Israel (Y. Maor, O. Schwartz); Kaplan Medical Center, Rehovot, Israel (O. Zimhony); Ariel University, Ariel, Israel (J. Lellouche).

Main Article

Figure 5

Comparison of antifungal MIC distribution among Candida auris clades, Israel. Antifungal MICs were determined using Clinical Laboratory Standards Institute M27A3/S4 methodology, for fluconazole (A), voriconazole (B), amphotericin B (C), and anidulafungin (D). Comparison among C. auris clades was done using the Kruskal-Wallis test and the pairwise Wilcoxon post-hoc test. Each dot represents a patient-specific isolate. Horizontal bars within box plots indicate medians, box tops and bottoms represent 95% confidence interval. NS, not significant.

Figure 5. Comparison of antifungal MIC distribution among Candida auris clades, Israel. Antifungal MICs were determined using Clinical Laboratory Standards Institute M27A3/S4 methodology, for fluconazole (A), voriconazole (B), amphotericin B (C), and anidulafungin (D). Comparison among C. auris clades was done using the Kruskal-Wallis test and the pairwise Wilcoxon post-hoc test. Each dot represents a patient-specific isolate. Horizontal bars within box plots indicate medians, box tops and bottoms represent 95% confidence interval. NS, not significant.

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Main Article

1Preliminary results from this study were presented at the 32nd European Congress of Clinical Microbiology and Infectious Diseases, April 23–26, 2022, Lisbon, Portugal.

Page created: April 29, 2023
Page updated: June 20, 2023
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