Nationwide Outbreak of Candida auris Infections Driven by COVID-19 Hospitalizations, Israel, 2021–20221
Roni Biran, Regev Cohen, Talya Finn, Tal Brosh-Nissimov, Galia Rahav, Dafna Yahav, Sharon Amit, Yael Shachor-Meyouhas, Alaa Atamna, Jihad Bishara, Liat Ashkenazi-Hoffnung, Haim Ben Zvi, Mirit Hershman-Sarafov, Shlomo Maayan, Yasmin Maor, Orna Schwartz, Oren Zimhony, Jonathan Lellouche, Meital Elbaz, Ela Burdelova, Naama Mizrahi, Anna Novikov, Oryan Henig, and Ronen Ben-Ami
Author affiliations: Tel Aviv Sourasky Medical Center, Tel Aviv, Israel (R. Biran, M. Elbaz, E. Burdelova, N. Mizrahi, A. Novikov, O. Henig, R. Ben-Ami); Hillel Yaffe Medical Center, Hadera, Israel (R. Cohen); Technion, Haifa, Israel (R. Cohen, Y. Shachor-Meyouhas, M. Hershman-Sarafov); Sanz Medical Center, Netanya, Israel (T. Finn, J. Lellouche); Samson Assuta Ashdod University Hospital, Ashdod, Israel (T. Brosh-Nissimov); Ben Gurion University in the Negev, Beer Sheba, Israel (T. Brosh-Nissimov); Sheba Medical Center, Tel Hashomer, Israel (G. Rahav, D. Yahav, S. Amit); Tel Aviv University, Tel Aviv (G. Rahav, D. Yahav, A. Atamna, J. Bishara, L. Ashkenazi-Hoffnung, H. Ben Zvi, Y. Maor, R. Ben-Ami); Rambam Medical Center, Haifa (Y. Shachor-Meyouhas); Beilinson Hospital, Rabin Medical Center, Petach-Tikva, Israel (A. Atamna, J. Bishara); Schneider Children’s Medical Center, Petach-Tikva (L. Ashkenazi-Hoffnung); Bnai Zion Medical Center, Haifa (M. Hershman Sarafov); Barzilai Medical Center, Ashdod (S. Maayan); Hebrew University of Jerusalem, Jerusalem, Israel (S. Maayan, O. Zimhony); Wolfson Medical Center, Holon, Israel (Y. Maor, O. Schwartz); Kaplan Medical Center, Rehovot, Israel (O. Zimhony); Ariel University, Ariel, Israel (J. Lellouche).
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Figure 6
Figure 6. Temporal distribution of Candida auris clades and their respective MIC values, Israel. Distribution of C. auris fluconazole and voriconazole MIC is shown for January 2014–May 2022. Each dot represents a patient-specific isolate. High fluconazole and voriconazole MIC associated with clade III is noted in 2021 and 2022.
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