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Volume 29, Number 8—August 2023
Research

Economic Evaluation of Wastewater Surveillance Combined with Clinical COVID-19 Screening Tests, Japan

Byung-Kwang YooComments to Author , Ryo Iwamoto, Ungil Chung, Tomoko Sasaki, and Masaaki Kitajima
Author affiliations: Waseda University, Saitama, Japan (B.-K. Yoo); Kanagawa University of Human Services, Kanagawa, Japan (B.-K. Yoo, U. Chung); Shionogi & Co. Ltd. and AdvanSentinal Inc., Osaka, Japan (R. Iwamoto); The University of Tokyo, Tokyo, Japan (U. Chung); Independent consultant, Shiga, Japan (T. Sasaki); Hokkaido University, Hokkaido, Japan (M. Kitajima)

Main Article

Table 2

Base-case analysis with a deterministic model in an economic evaluation of wastewater surveillance combined with clinical COVID-19 screening tests, Japan*

Table 2. Base-case analysis with a deterministic model in an economic evaluation of wastewater surveillance combined with clinical COVID-19 screening tests, Japan*
Incidence† Option 1
 Option 2
 Relative value of option 2
Cost Benefit ROI‡ Cost Benefit ROI‡ Incremental cost§ Incremental benefit¶ Relative ROI#
10 $67.04 $1.39 0.021 $53.60 $1.14 0.021 –$13.44 –$0.25 54
100 $67.05 $14.09 0.21 $53.61 $11.94 0.22 –$13.43 –$2.15 6.25
1,000 $67.12 $141.11 2.10 $53.75 $119.94 2.23 –$13.37 –$21.16 0.63

*Option 1 is clinical testing only; option 2 is wastewater surveillance and clinical testing. If one option is cost-saving compared with its comparator, the option’s ROI is estimated to exceed 1. The comparator of options 1 and 2 is do-nothing. All monetary values are expressed in 2022 US dollars (USD). ROI, return on investment. †Disease incidence per day per 1 million residents in the area. ‡ROI is benefit divided by cost for each option. §Incremental cost is the cost of option 2 minus cost of option 1. A negative value of incremental cost indicates that option 2 has a lower cost or is cost-saving, compared with option 1. This could be interpreted as option 2’s relative benefit. ¶Incremental benefit is the benefit of option 2 minus benefit of option 1. A negative value of incremental benefit indicates that option 2 has a lower benefit compared with option 1, which could be interpreted as option 2’s relative cost. #Relative ROI is incremental cost divided by incremental benefit.

Main Article

Page created: June 02, 2023
Page updated: July 20, 2023
Page reviewed: July 20, 2023
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