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Volume 29, Number 8—August 2023
Research

Multidrug-Resistant Bacterial Colonization and Infections in Large Retrospective Cohort of Mechanically Ventilated COVID-19 Patients1

Davide Mangioni, Liliane Chatenoud, Jacopo Colombo, Emanuele Palomba, Fernando A. Guerrero, Matteo Bolis, Nicola Bottino, Giuseppe Breda, Maria V. Chiaruttini, Gabriele Fior, Manuela Marotta, Giovanni Massobrio, Caterina Matinato, Antonio Muscatello, Paola Previtali, Sara Santambrogio, Francesca Tardini, Gianluca Zuglian, Giacomo Grasselli, Roberto Fumagalli, Andrea Gori, Nino Stocchetti, Gianpaola Monti2, Alessandra Bandera2, and the MDR in FIERA Study Group3
Author affiliations: Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy (D. Mangioni, E. Palomba, M. Bolis, N. Bottino, G. Breda, G. Massobrio, C. Matinato, A. Muscatello, G. Zuglian, G. Grasselli, A. Gori, N. Stocchetti, A. Bandera); University of Milan, Milan (D. Mangioni, E. Palomba, G. Grasselli, A. Gori, N. Stocchetti, A, Bandera); Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan (L. Chatenoud, M.V. Chiaruttini); Harvard Medical School, Boston, Massachusetts, USA (J. Colombo); ASST Grande Ospedale Metropolitano Niguarda, Milan (J. Colombo, F.A. Guerrero, G. Fior, M. Marotta, P. Previtali, S. Santambrogio, F. Tardini, R. Fumagalli, G. Monti); ULSS 3 Serenissima, Venice, Italy (G. Zuglian); University of Milano-Bicocca, Milan (R. Fumagalli)

Main Article

Figure 2

Study flowchart showing microbial isolates selection process for multidrug-resistant bacterial colonization and infections in large retrospective cohort of COVID-19 mechanically ventilated patients admitted to ICU in Milan, Italy, October 2020–May 2021. ETA, emergency treatment area; ICU, intensive care unit; MDR, multidrug resistant; MDRO, multidrug-resistant organism. *Of 338 patients, 159 (47.0%) had either MDRO or non-MDRO infections; 74/338 (21.9%) had both MDRO and non-MDRO infections.

Figure 2. Study flowchart showing microbial isolates selection process for multidrug-resistant bacterial colonization and infections in large retrospective cohort of COVID-19 mechanically ventilated patients admitted to ICU in Milan, Italy, October 2020–May 2021. ETA, emergency treatment area; ICU, intensive care unit; MDR, multidrug resistant; MDRO, multidrug-resistant organism. *Of 338 patients, 159 (47.0%) had either MDRO or non-MDRO infections; 74/338 (21.9%) had both MDRO and non-MDRO infections.

Main Article

1Preliminary results were presented at the European Congress of Clinical Microbiology and Infectious Diseases, 2022, Lisbon, Portugal, April 23‒26, 2022 (abstract no. 02641).

2These senior authors contributed equally to this article.

3Study group members are listed at the end of this article.

Page created: June 22, 2023
Page updated: July 20, 2023
Page reviewed: July 20, 2023
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